Evidence map›Paper›PMID 23625316›Full record

ReviewCurrent neurology and neuroscience reports2013

Freezing of gait in Parkinson's disease: where are we now?

Elke Heremans, Alice Nieuwboer, Sarah Vercruysse

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Current neurology and neuroscience reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05080413 (Comparison of Sensory Cuing Modalities for Freezing of Gait in Patients With Idiopathic Parkinson's Disease), which is not on this map. Cited by 74 papers.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05080413 nacompletednot on this mapstarted 2020, after this paper: background citation

Comparison of Sensory Cuing Modalities for Freezing of Gait in Patients With Idiopathic Parkinson's Disease : a Pilot Study

TypeinterventionalSponsorVeterans Health Service Medical Center, Seoul, KoreaRan2020 to 2021Enrolled10ConditionsParkinson DiseaseArmsLaser shoes, Metronome
3 · Its place in the literature

Who cites it

74 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Functional Improvements in Parkinson's Disease Following a Randomized Trial of Yoga.Evidence-based complementary and alternative medicine : eCAM · 2018
    Trial
  4. Trial
  5. Article
  6. Article
  7. Effects of Cueing Training on Gait Variability.International journal of exercise science · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Vibration stimulation to the lower limbs improves freezing of gait and modifies cortical electrical activities in Parkinson's disease.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article

14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Elke HeremansDepartment of Rehabilitation Sciences, Katholieke Universiteit Leuven, Leuven, Belgium. elke.heremans@faber.kuleuven.be
Alice Nieuwboer
Sarah Vercruysse

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Freezing of gait (FOG) is defined as a brief, episodic absence or marked reduction of forward progression of the feet despite the intention to walk. It is one of the most debilitating motor symptoms in patients with Parkinson's disease (PD) as it may lead to falls and a loss of independence. The pathophysiology of FOG seems to differ from the cardinal features of PD and is still largely unknown. In the present paper, we review the studies that were performed since 2011 on methods to provoke and assess FOG and discuss new insights into behavioral and neural mechanisms underlying this clinical phenomenon. We conclude that most of the work reviewed confirms that gait pattern generation disturbances are central to FOG. The finding that FOG reflects a combined motor and cognitive de-automatization deficit, which may not be sufficiently offset by executive control, probably acts as parallel mechanism.

Indexed as

Cognition DisordersFreezing Reaction, CatalepticGait Disorders, NeurologicHumansParkinson DiseasePerceptual DisordersPostural BalanceRadionuclide Imaging

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.