Evidence map›Paper›PMID 23625271›Full record

ReviewCurrent hypertension reports2013

Pharmacologic treatment options for obesity: what is old is new again.

Donna H Ryan, George A Bray

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Current hypertension reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04725058 (Obesity Group Visits. A Novel Way to Approach the Obesity Epidemic in an Inner-City Setting), which is not on this map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04725058 naactive not recruitingnot on this mapstarted 2020, after this paper: background citation

Obesity Group Visits. A Novel Way to Approach the Obesity Epidemic in an Inner-City Setting

TypeinterventionalSponsorCharles Drew University of Medicine and ScienceRan2020 to 2025Enrolled1,000ConditionsObesityArmsMedical Group Visit, Dietitian Individual Visit
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Review
  7. Observational
  8. Observational
  9. Review
  10. Review
  11. Review
  12. Article
  13. Pharmacotherapy for obesity: novel agents and paradigms.Therapeutic advances in chronic disease · 2014
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Donna H RyanPennington Biomedical Research Center, 6400 Perkins Road, Baton Rouge, LA 70808, USA. ryandh@pbrc.edu
George A Bray
Pennington Biomedical Research Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

After a long period of failure in development, two new medications (phentermine/topiramate ER - Qsymia™ and lorcaserin - Belviq®) have been approved by the US Food and Drug Administration for long-term weight management in persons with obesity (BMI ≥ 30 kg/m(2)) or in overweight persons (BMI ≥ 27 kg/m(2)) with comorbidities. Another medication, bupropion/naltrexone, is undertaking a cardiovascular outcomes trial and an analysis in 2014 will determine its approval and release. The most widely prescribed drug for obesity, phentermine, used since 1959 for short-term weight management, has been released in a new formulation. This paper reviews these new medications, and other important events in the landscape for management of obesity, with an eye to the interests of physicians who manage hypertension. All the new drugs under discussion are re-fittings of old agents or fresh approaches to old targets; thus, what is old is new again in the pharmacotherapy of obesity.

Indexed as

Anti-Obesity AgentsAppetite DepressantsHumansObesityTimeWeight LossAnti-Obesity AgentsAppetite Depressants

Identifiers

PMID23625271
OpenAlexW2086891999

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.