ArticleDevelopment genes and evolution2013
The expression pattern of the genes engrailed, pax6, otd and six3 with special respect to head and eye development in Euperipatoides kanangrensis Reid 1996 (Onychophora: Peripatopsidae).
Article in Development genes and evolution, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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25 citing papers in PubMed, 65 citations in OpenAlex.
- Anterior-posterior patterning in the chaetognath Spadella cephaloptera informs bilaterian nervous system and tail evolution.Communications biology · 2025Article
- DuplicatedBiology · 2025Article
- Organ systems of a Cambrian euarthropod larva.Nature · 2024Article
- Unfolding the ventral nerve center of chaetognaths.Neural development · 2024Article
- Article
- Expression of NK genes that are not part of the NK cluster in the onychophoran Euperipatoides rowelli (Peripatopsidae).BMC developmental biology · 2019Article
- Phylogenetic analysis and embryonic expression of panarthropod Dmrt genes.Frontiers in zoology · 2019Article
- Embryonic expression patterns and phylogenetic analysis of panarthropod sox genes: insight into nervous system development, segmentation and gonadogenesis.BMC evolutionary biology · 2018Article
- Comparison of ventral organ development across Pycnogonida (Arthropoda, Chelicerata) provides evidence for a plesiomorphic mode of late neurogenesis in sea spiders and myriapods.BMC evolutionary biology · 2018Article
- Brain and eyes of Kerygmachela reveal protocerebral ancestry of the panarthropod head.Nature communications · 2018Article
- Expression of six3 and otx in Solenogastres (Mollusca) supports an ancestral role in bilaterian anterior-posterior axis patterning.Evolution & development · 2018Article
- Expression of NK cluster genes in the onychophoranEvoDevo · 2018Article
- Article
- The nervous and visual systems of onychophorans and tardigrades: learning about arthropod evolution from their closest relatives.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2017Review
- Ancestral and novel roles of Pax family genes in mollusks.BMC evolutionary biology · 2017Article
- Article
- An embryological perspective on the early arthropod fossil record.BMC evolutionary biology · 2015Article
- Insights into the segmental identity of post-oral commissures and pharyngeal nerves in Onychophora based on retrograde fills.BMC neuroscience · 2015Article
- Engrailed homeoproteins in visual system development.Cellular and molecular life sciences : CMLS · 2015Review
- The evolution of early neurogenesis.Developmental cell · 2015Review
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3 authors at 1 institution in 1 country.
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Abstract
The genes otd/otx, six3, pax6 and engrailed are involved in eye patterning in many animals. Here, we describe the expression pattern of the homologs to otd/otx, six3, pax6 and engrailed in the developing Euperipatoides kanangrensis embryos. Special reference is given to the expression in the protocerebral/ocular region. E. kanangrensis otd is expressed in the posterior part of the protocerebral/ocular segment before, during and after eye invagination. E. kanangrensis otd is also expressed segmentally in the developing ventral nerve cord. The E. kanangrensis six3 is located at the extreme anterior part of the protocerebral/ocular segment and not at the location of the developing eyes. Pax6 is expressed in a broad zone at the posterior part of the protocerebral/ocular segment but only weak expression can be seen at the early onset of eye invagination. In late stages of development, the expression in the eye is upregulated. Pax6 is also expressed in the invaginating hypocerebral organs, thus supporting earlier suggestions that the hypocerebral organs in onychophorans are glands. Pax6 transcripts are also present in the developing ventral nerve cord. The segment polarity gene engrailed is expressed at the dorsal side of the developing eye including only a subset of the cells of the invaginating eye vesicle. We show that engrailed is not expressed in the neuroectoderm of the protocerebral/ocular segment as in the other segments. In addition, we discuss other aspect of otd, six3 and pax6 expression that are relevant to our understanding of evolutionary changes in morphology and function in arthropods.
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