ArticleInternational journal of molecular sciences2013
Tumour cell labelling by magnetic nanoparticles with determination of intracellular iron content and spatial distribution of the intracellular iron.
Article in International journal of molecular sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Determination of core and shell radii of individual core-shell magnetic nanoparticles by magnetic force microscopy.Nanoscale advances · 2026Article
- Imaging beyond the surface region: Probing hidden materials via atomic force microscopy.Science advances · 2023Review
- Synthesis and Characterization of Citric Acid-Modified Iron Oxide Nanoparticles Prepared with Electrohydraulic Discharge Treatment.Materials (Basel, Switzerland) · 2023Article
- New Approach to Non-Invasive Tumor Model Monitoring via Self-Assemble Iron Containing Protein Nanocompartments.Nanomaterials (Basel, Switzerland) · 2022Article
- Nano-Scale Zero Valent Iron (nZVI) Priming Enhances Yield, Alters Mineral Distribution and Grain Nutrient Content ofJournal of plant growth regulation · 2022Article
- Treatment of Breast Cancer-Bearing BALB/c Mice with Magnetic Hyperthermia using Dendrimer Functionalized Iron-Oxide Nanoparticles.Nanomaterials (Basel, Switzerland) · 2020Article
- The Potential of Intrinsically Magnetic Mesenchymal Stem Cells for Tissue Engineering.International journal of molecular sciences · 2018Review
- Tenacic Acids: A New Class of Tenacious Binders to Metal Oxide Surfaces.Chemistry (Weinheim an der Bergstrasse, Germany) · 2018Article
- Biosynthesis of magnetic nanoparticles by human mesenchymal stem cells following transfection with the magnetotactic bacterial gene mms6.Scientific reports · 2017Article
- Quantitative [Fe]MRI of PSMA-targeted SPIONs specifically discriminates among prostate tumor cell types based on their PSMA expression levels.International journal of nanomedicine · 2016Article
- g-force induced giant efficiency of nanoparticles internalization into living cells.Scientific reports · 2015Article
- In Vitro/In Vivo Toxicity Evaluation and Quantification of Iron Oxide Nanoparticles.International journal of molecular sciences · 2015Review
- In Vivo Molecular MRI Imaging of Prostate Cancer by Targeting PSMA with Polypeptide-Labeled Superparamagnetic Iron Oxide Nanoparticles.International journal of molecular sciences · 2015Article
- Characterization of interaction of magnetic nanoparticles with breast cancer cells.Journal of nanobiotechnology · 2015Article
- Highly Efficient Labeling of Human Lung Cancer Cells Using Cationic Poly-l-lysine-Assisted Magnetic Iron Oxide Nanoparticles.Nano-micro letters · 2015Article
- Antibody-conjugated paramagnetic nanobeads: kinetics of bead-cell binding.International journal of molecular sciences · 2014Article
- Sheets of vertically aligned BaTiO3 nanotubes reduce cell proliferation but not viability of NIH-3T3 cells.PloS one · 2014Article
- Magnetic force microscopy: quantitative issues in biomaterials.Biomatter · 2014Article
- The effect of superparamagnetic iron oxide with iRGD peptide on the labeling of pancreatic cancer cells in vitro: a preliminary study.BioMed research international · 2014Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Magnetically labelled cells are used for in vivo cell tracking by MRI, used for the clinical translation of cell-base therapies. Studies involving magnetic labelled cells may include separation of labelled cells, targeted delivery and controlled release of drugs, contrast enhanced MRI and magnetic hyperthermia for the in situ ablation of tumours. Dextran-coated super-paramagnetic iron oxide (SPIO) ferumoxides are used clinically as an MR contrast agents primarily for hepatic imaging. The material is also widely used for in vitro cell labelling, as are other SPIO-based particles. Our results on the uptake by human cancer cell lines of ferumoxides indicate that electroporation in the presence of protamine sulphate (PS) results in rapid high uptake of SPIO nanoparticles (SPIONs) by parenchymal tumour cells without significant impairment of cell viability. Quantitative determination of cellular iron uptake performed by colorimetric assay is in agreement with data from the literature. These results on intracellular iron content together with the intracellular distribution of SPIONs by magnetic force microscopy (MFM) following in vitro uptake by parenchymal tumour cells confirm the potential of this technique for clinical tumour cell detection and destruction.
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