ArticleNature genetics2013
The draft genomes of soft-shell turtle and green sea turtle yield insights into the development and evolution of the turtle-specific body plan.
Article in Nature genetics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 193 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
193 citing papers in PubMed.
- Genomic Distortion of Jawed Vertebrate Phylogeny.bioRxiv : the preprint server for biology · 2026Article
- Internalized Evolutionary Inertia on Body Plan Evolution.Evolution & development · 2026Review
- The genomic basis of independent marine transitions in turtles: convergent episodic adaptation and demographic shifts.Molecular biology and evolution · 2026Article
- Article
- A comprehensive embryonic staging series of the turtle Trachemys scripta.Developmental dynamics : an official publication of the American Association of Anatomists · 2026Article
- Toward mechanisms underlying the developmental hourglass: evolvability and phylotypic conservation.EvoDevo · 2025Review
- Chromosome-level genome assembly of the Chinese soft-shelled turtle Pelodiscus sinensis.Scientific data · 2025Article
- Transcriptome data from the interdigital webs of the Chinese Soft-shell Turtle (Pelodiscus sinensis).Scientific data · 2025Article
- Green Turtle Conservation in the Genomic Era-Monitoring an Endangered Mediterranean Population and Its Breeding Habits.Ecology and evolution · 2025Article
- Genomic insights into marine environment adaptation and conservation of the threatened olive ridley turtle (iScience · 2025Article
- Chromosome-level genome assembly and methylome profile yield insights for the conservation of endangered loggerhead sea turtles.GigaScience · 2025Article
- The Importance of Olfaction for Mixed Paternity in Birds.Ecology and evolution · 2025Article
- Genome-wide identification and expression profiling of the Wnt gene family in three abalone species.Genes & genomics · 2024Review
- Sex-Dimorphic Differential Expression Profiles in the Brain of the Adult Chinese Soft-Shelled Turtle,Animals : an open access journal from MDPI · 2024Article
- De novo genome assemblies of two cryptodiran turtles with ZZ/ZW and XX/XY sex chromosomes provide insights into patterns of genome reshuffling and uncover novel 3D genome folding in amniotes.Genome research · 2024Article
- slc26a12-A novel member of the slc26 family, is located in tandem with slc26a2 in coelacanths, amphibians, reptiles, and birds.Physiological reports · 2024Article
- Multiple horizontal transfer events of a DNA transposon into turtles, fishes, and a frog.Mobile DNA · 2024Article
- A chromosome-level genome assembly of the pig-nosed turtle (Carettochelys insculpta).Scientific data · 2024Article
- Developmental hourglass: Verification by numerical evolution and elucidation by dynamical-systems theory.PLoS computational biology · 2024Article
- Identification of Sex-Specific Markers and Candidate Genes Using WGS Sequencing Reveals a ZW-Type Sex-Determination System in the Chinese Soft-Shell Turtle (International journal of molecular sciences · 2024Article
133 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
- Commented on byTurtle ghrelin.2014
- Commented on byTurtle ghrelin.2014
- Commented on byTurtle ghrelin.2014
- Erratum issued
Authors and funding
34 authors.
Funding
Abstract
The unique anatomical features of turtles have raised unanswered questions about the origin of their unique body plan. We generated and analyzed draft genomes of the soft-shell turtle (Pelodiscus sinensis) and the green sea turtle (Chelonia mydas); our results indicated the close relationship of the turtles to the bird-crocodilian lineage, from which they split ∼267.9-248.3 million years ago (Upper Permian to Triassic). We also found extensive expansion of olfactory receptor genes in these turtles. Embryonic gene expression analysis identified an hourglass-like divergence of turtle and chicken embryogenesis, with maximal conservation around the vertebrate phylotypic period, rather than at later stages that show the amniote-common pattern. Wnt5a expression was found in the growth zone of the dorsal shell, supporting the possible co-option of limb-associated Wnt signaling in the acquisition of this turtle-specific novelty. Our results suggest that turtle evolution was accompanied by an unexpectedly conservative vertebrate phylotypic period, followed by turtle-specific repatterning of development to yield the novel structure of the shell.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.