ArticleBrain, behavior, and immunity2013
Inflammatory biomarkers and emotional approach coping in men with prostate cancer.
Article in Brain, behavior, and immunity, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- The utility of coping through emotional approach: A meta-analysis.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2024Pooled it
- A systematic review of associations between emotion regulation characteristics and inflammation.Neuroscience and biobehavioral reviews · 2023Pooled it
- Prognostic role of C-reactive protein in prostate cancer: a systematic review and meta-analysis.Asian journal of andrologyPooled it
- A Randomized Controlled Trial of Goal-Focused Emotion-Regulation Therapy for Young Adult Survivors of Testicular Cancer: Effects on Salivary and Inflammatory Stress Markers.American journal of men's healthTrial
- Sex differences in the association of emotional approach coping with stress and quality of life among patients with renal cell carcinoma.Palliative & supportive care · 2026Article
- The Inflammatory Footprint of Anti-Breast Cancer Treatments and Psychosocial Factors in Women Undergoing Chemotherapy.Biomedicines · 2025Article
- Contributing factors to well-being in a sample of long-term survivors of childhood acute lymphoblastic leukemia: the role of social support in emotional regulation.Health psychology and behavioral medicine · 2024Article
- The influence of lifestyle changes (diet, exercise and stress reduction) on prostate cancer tumour biology and patient outcomes: A systematic review.BJUI compass · 2023Review
- Relationship Between Longitudinal Coping Strategies and Outcomes in Patients With Acute Myeloid Leukemia.Journal of the National Comprehensive Cancer Network : JNCCN · 2022Article
- FAM64A is an androgen receptor-regulated feedback tumor promoter in prostate cancer.Cell death & disease · 2021Article
- Transitions in coping profiles after breast cancer diagnosis: implications for depressive and physical symptoms.Journal of behavioral medicine · 2021Article
- Emotions matter: The role of emotional approach coping in chronic pain.European journal of pain (London, England) · 2020Article
- Emotional approach coping in older adults as predictor of physical and mental health.Psychology and aging · 2020Article
- Positive and Negative Affect and Salivary Markers of Inflammation Among Young Adults.International journal of behavioral medicine · 2020Article
- Article
- Physician Empathy Interacts with Breaking Bad News in Predicting Lung Cancer and Pleural Mesothelioma Patient Survival: Timing May Be Crucial.Journal of clinical medicine · 2018Article
- Emotions and Emotion Regulation in Breast Cancer Survivorship.Healthcare (Basel, Switzerland) · 2016Review
- Approach and avoidance coping: diurnal cortisol rhythm in prostate cancer survivors.Psychoneuroendocrinology · 2014Article
- Emotional approach coping and depressive symptoms in colorectal cancer patients: The role of the intimate relationship.Journal of psychosocial oncologyArticle
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
objectiveEmotion-regulating coping is associated with improvements in psychological and physical health outcomes. Yet in the context of prostate cancer-related stressors, limited research has characterized associations of emotion-regulating coping processes (emotional expression, emotional processing) and inflammatory processes that are related to disease risk. This investigation examined the relation of Emotional Approach Coping (EAC) with markers of inflammation to test the hypothesis that higher EAC scores at study entry (T1) would be associated with lower proinflammatory markers four months later (T2), specifically sTNF-RII, CRP, and IL-6.
methodsForty-one men (M age=66.62 years; SD=9.62) who had undergone radical prostatectomy or radiation therapy for localized prostate cancer within two years completed questionnaires, including assessments of EAC, at T1, and provided blood samples for immune assessments at T2.
resultsWhen controlling for relevant biobehavioral controls, emotional processing predicted lower IL-6 (B=-.66, p<.01), sTNF-RII (B=-.43, p<.05), and CRP (B=-.43, p<.10), whereas emotional expression was significantly associated with higher levels of sTNF-RII (B=.55, p<.05). Associations of emotional expression and IL-6 (B=.38, p<.10), and CRP (B=.44, p<.10) approached significance. Probing interactions of emotional processing and expression (though only approaching significance) suggested that expression of emotion is associated with higher inflammation (CRP and sTNF-RII) only in the context of low emotional processing.
conclusionsAttempts at emotion regulation via emotional processing appear to modulate inflammatory processes. Understanding, making meaning of, and working through emotional experience may be a promising target of intervention to reduce inflammation with potential effects on psychological and cancer outcomes in men with prostate cancer.
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