ReviewPhysiology & behavior2013
Sex differences and chronic stress effects on the neural circuitry underlying fear conditioning and extinction.
Review in Physiology & behavior, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
39 citing papers in PubMed, 73 citations in OpenAlex.
- Chronic stress enhances threat responding and impacts fear extinction.Learning & memory (Cold Spring Harbor, N.Y.) · 2026Article
- Exploring the impact of biological sex on intrinsic connectivity networks in PTSD: A data-driven approach.Progress in neuro-psychopharmacology & biological psychiatry · 2025Article
- Sex-biased neural encoding of threat discrimination in nucleus accumbens afferents drives suppression of reward behavior.Nature neuroscience · 2024Article
- Data-driven, connectome-wide analysis identifies psychosis-specific brain correlates of fear and anxiety.Molecular psychiatry · 2024Article
- Acute stress yields a sex-dependent facilitation of signaled active avoidance in rats.Neurobiology of stress · 2024Review
- Acute stress yields a sex-dependent facilitation of signaled active avoidance in rats.bioRxiv : the preprint server for biology · 2024Article
- Article
- Heterotypic Stressors Unmask Behavioral Influences of PMAT Deficiency in Mice.International journal of molecular sciences · 2023Article
- Heterotypic stressors unmask behavioral influences of PMAT deficiency in mice.bioRxiv : the preprint server for biology · 2023Article
- Dopamine-Dependent Ketamine Modulation of Glutamatergic Synaptic Plasticity in the Prelimbic Cortex of Adult Rats Exposed to Acute Stress.International journal of molecular sciences · 2023Article
- The sex-dependent response to psychosocial stress and ischaemic heart disease.Frontiers in cardiovascular medicine · 2023Review
- Male and female mice display consistent lifelong ability to address potential life-threatening cues using different post-threat coping strategies.BMC biology · 2022Article
- Review
- Sex differences in the delayed impact of acute stress on the amygdala.Neurobiology of stress · 2021Article
- Comparison of cannabidiol to citalopram in targeting fear memory in female mice.Journal of cannabis research · 2020Article
- Activation of Infralimbic to Nucleus Accumbens Shell Pathway Suppresses Conditioned Aversion in Male But Not Female Rats.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Evidence for Similar Prefrontal Structural and Functional Alterations in Male and Female Rats Following Chronic Stress or Glucocorticoid Exposure.Cerebral cortex (New York, N.Y. : 1991) · 2020Article
- Sex-Related Differential Whole-Brain Input Atlas of Locus Coeruleus Noradrenaline Neurons.Frontiers in neural circuits · 2020Article
- Sex Differences in the Development of the Rodent Corticolimbic System.Frontiers in neuroscience · 2020Review
- Timing is everything: differential effects of chronic stress on fear extinction.Psychopharmacology · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
There are sex differences in the rates of many stress-sensitive psychological disorders such as posttraumatic stress disorder (PTSD). As medial prefrontal cortex and amygdala are implicated in many of these disorders, understanding differential stress effects in these regions may shed light on the mechanisms underlying sex-dependent expression of disorders like depression and anxiety. Prefrontal cortex and amygdala are key regions in the neural circuitry underlying fear conditioning and extinction, which thus has emerged as a useful model of stress influences on the neural circuitry underlying regulation of emotional behavior. This review outlines the current literature on sex differences and stress effects on dendritic morphology within medial prefrontal cortex and basolateral amygdala. Such structural differences and/or alterations can have important effects on fear conditioning and extinction, behaviors that are mediated by the basolateral amygdala and prefrontal cortex, respectively. Given the importance of extinction-based exposure therapy as a treatment for anxiety disorders such as PTSD, understanding the neural mechanisms by which stress differentially influences fear learning and extinction in males and females is an important goal for developing sex-appropriate interventions for stress-related disorders.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.