ArticleAmerican heart journal2013
Saphenous vein graft failure and clinical outcomes: toward a surrogate end point in patients following coronary artery bypass surgery?
Article in American heart journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The association between coronary graft patency and clinical status in patients with coronary artery disease.European heart journal · 2021Pooled it
- Choice of vein-harvest technique for coronary artery bypass grafting: rationale and design of the REGROUP trial.Clinical cardiology · 2014Trial
- The Role of Preoperative CHA2DS2-VASc Score in Predicting Late Saphenous Vein Graft Failure in Non-STEMI Patients with Prior Coronary Artery Bypass Grafting: A Retrospective Study.Sisli Etfal Hastanesi tip bulteni · 2025Article
- Multimodal Data-Driven Prognostic Model for Predicting Long-Term Prognosis in Patients With Ischemic Cardiomyopathy and Heart Failure With Preserved Ejection Fraction After Coronary Artery Bypass Grafting: A Multicenter Cohort Study.Journal of the American Heart Association · 2024Article
- Consensus statement-graft treatment in cardiovascular bypass graft surgery.Frontiers in cardiovascular medicine · 2024Article
- Bleeding risk in patients prescribed dual antiplatelet therapy and triple therapy after coronary interventions: the ADAPTT retrospective population-based cohort studies.Health technology assessment (Winchester, England) · 2023Article
- Long-Term Survival of Multiple Versus Single Arterial Coronary Bypass Grafting in Elderly Patients.Journal of clinical medicine · 2023Article
- Late Clinical Outcomes of Total Arterial Revascularization or Multiple Arterial Grafting Compared to Conventional Single Arterial with Saphenous Vein Grafting for Coronary Surgery.Journal of clinical medicine · 2023Review
- The impact of the quantitative assessment procedure for coronary artery bypass graft evaluations using high-resolution near-infrared fluorescence angiography.Surgery today · 2022Article
- Association of hypoxia and mitochondrial damage associated molecular patterns in the pathogenesis of vein graft failure: a pilot study.Translational research : the journal of laboratory and clinical medicine · 2021Article
- Wire Perforation or Coronary-Cameral Fistula? A Diagnostic Dilemma Complicating a Case of ST-Segment Elevation Myocardial Infarction.CASE (Philadelphia, Pa.) · 2018Article
- Pilot assessment of a human extracellular matrix-based vascular graft in a rabbit model.Journal of vascular surgery · 2017Article
- Increased Contractile Function of Human Saphenous Vein Grafts Harvested by "No-Touch" Technique.Frontiers in physiology · 2017Article
- Meaningful outcome measures in cardiac surgery.The journal of extra-corporeal technology · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Saphenous vein graft (SVG) failure is a common finding in patients following coronary artery bypass graft (CABG) surgery. In the literature SVG failure rates have been reported from 25 to over 50% within 10 years. Although common, it remains unclear to what extent SVG failure affects clinical outcome, due to differences in definition, patient selection and follow-up. Particularly the lack of agreement on a universal definition makes comparisons between studies, and therefore generalizability of associations with outcomes, challenging. We suggest using a definition of SVG failure that is based on imaging as well as clinical parameters, that includes reporting SVG failure on both graft and patient level. The use of non-invasive imaging may help improve follow-up rates, and provide a more accurate picture of the real incidence and clinical impact of SVG failure. Given the lack of supportive evidence showing a consistent association between SVG failure and major adverse cardiovascular events, SVG failure should not be considered a valid surrogate endpoint at this time.
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Registered trials
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