ArticleScandinavian journal of primary health care2013
The prevalence of potential alcohol-drug interactions in older adults.
Article in Scandinavian journal of primary health care, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 63 citations in OpenAlex.
- A systematic review of self-report measures used in epidemiological studies to assess alcohol consumption among older adults.PloS one · 2021Pooled it
- Concurrent use of alcohol interactive medications and alcohol in older adults: a systematic review of prevalence and associated adverse outcomes.BMC geriatrics · 2017Pooled it
- Alcohol-medication interactions among older people: a narrative review on age-specific evidence.Alcohol and alcoholism (Oxford, Oxfordshire) · 2026Review
- Drug interactions in patients with alcohol use disorder: results from a real-world study on an addiction-specific ward.Therapeutic advances in drug safety · 2025Article
- Influence of inpatient withdrawal treatment on drug safety in alcohol use disorder - a quasi-experimental pre-post study.BMC psychiatry · 2024Article
- Drug safety in older patients with alcohol use disorder: a retrospective cohort study.Therapeutic advances in psychopharmacology · 2024Article
- Alcohol consumption and associations with sociodemographic and health-related characteristics in Germany: A population survey.Addictive behaviors · 2022Article
- Development of a Physiologically Based Pharmacokinetic Model for Prediction of Ethanol Concentration-Time Profile in Different Organs.Alcohol and alcoholism (Oxford, Oxfordshire) · 2021Article
- Cross-country differences in age trends in alcohol consumption among older adults: a cross-sectional study of individuals aged 50 years and older in 22 countries.Addiction (Abingdon, England) · 2021Observational
- Cross-country and historical variation in alcohol consumption among older men and women: Leveraging recently harmonized survey data in 21 countries.Drug and alcohol dependence · 2020Article
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- Potentially serious alcohol-medication interactions and falls in community-dwelling older adults: a prospective cohort study.Age and ageing · 2019Article
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- Longitudinal prevalence of potentially serious alcohol-medication interactions in community-dwelling older adults: a prospective cohort study.European journal of clinical pharmacology · 2019Article
- A comparison of hippocampal microglial responses in aged and young rodents following dependent and non-dependent binge drinking.International review of neurobiology · 2019Article
- Immediate effects of a brief intervention to prevent alcohol and medication interactions among older adults.Health education research · 2018Article
- 'I take my tablets with the whiskey': A qualitative study of alcohol and medication use in mid to later life.PloS one · 2018Article
- Trends in polypharmacy over 12 years and changes in its social gradients in South Korea.PloS one · 2018Article
- Sustained Intervention Effects on Older Adults' Attitudes Towards Alcohol and Medication Interactions.American journal of health education · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe aim of this study was to assess the possibility of clinically significant drug-alcohol interactions among home-dwelling older adults aged ≥ 65 years.
designThis study was a cross-sectional assessment of a stratified random sample of 2100 elderly people (≥ 65 years) in Espoo, Finland. The response rate was 71.6% from the community-dwelling sample. The drugs were coded according to their Anatomical Therapeutic Chemical (ATC) classification index (ATC DDD 2012). Significant alcohol interactive (AI) drugs were examined according to the Swedish, Finnish, INteraction X-referencing (SFINX) interaction database, as well as concomitant use of central nervous system drugs, hypoglycaemics, and warfarin with alcohol. "At-risk alcohol users" were defined consuming > 7 drinks/week, or ≥ 5 drinks on a typical drinking day, or using ≥ 3 drinks several times/week, "moderate users" as consuming at least one drink/month, but less than 7 drinks/week, and "minimal/non-users" less than one drink/month.
resultsOf the total sample (n = 1395), 1142 respondents responded as using at least one drug. Of the drug users, 715 (62.6%) persons used alcohol. The mean number of medications was 4.2 (SD 2.5) among "at-risk users", 4.0 (SD 2.6) among "moderate users", and 5.4 (SD 3.4) among "minimal/non-users" (p < 0.001). The concomitant use of AI drugs was widespread. Among the "at-risk users", "moderate users", and "minimal/nonusers" 42.2%, 34.9%, and 52.7%, respectively, were on AI drugs (p < 0.001). One in 10 of "at-risk users" used warfarin, hypnotics/sedatives, or metformin.
conclusionsUse of AI drugs is common among older adults, and this increases the potential risks related to the use of alcohol.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.