SynthesisPloS one2013
Efficacy of Tai Chi on pain, stiffness and function in patients with osteoarthritis: a meta-analysis.
Synthesis in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 9 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
44 citing papers in PubMed, 9 syntheses or guidelines pooled it.
- A systematic review and meta-analysis of the mechanism of action of Tai Chi on cardiovascular disease: evidence map of aerobic and mind-body exercise pathways.Scientific reports · 2026Pooled it
- Comparative effectiveness of traditional Chinese exercises for knee osteoarthritis: a systematic review and Bayesian network meta-analysis.Frontiers in public health · 2025Pooled it
- Tai Chi for rheumatoid arthritis.The Cochrane database of systematic reviews · 2019Pooled it
- Tai chi for treating osteopenia and primary osteoporosis: a meta-analysis and trial sequential analysis.Clinical interventions in aging · 2019Pooled it
- Health benefits of tai chi: What is the evidence?Canadian family physician Medecin de famille canadien · 2016Pooled it
- An evidence map of the effect of Tai Chi on health outcomes.Systematic reviews · 2016Pooled it
- Tai Chi for Chronic Pain Conditions: A Systematic Review and Meta-analysis of Randomized Controlled Trials.Scientific reports · 2016Pooled it
- The effect of Tai Chi training on cardiorespiratory fitness in healthy adults: a systematic review and meta-analysis.PloS one · 2015Pooled it
- Pooled it
- The Benefits ofJournal of alternative and complementary medicine (New York, N.Y.) · 2020Trial
- Effect of Tai Chi on Cardiac and Static Pulmonary Function in Older Community-Dwelling Adults at Risk of Ischemic Stroke: A Randomized Controlled Trial.Chinese journal of integrative medicine · 2019Trial
- Subjective perceived impact of Tai Chi training on physical and mental health among community older adults at risk for ischemic stroke: a qualitative study.BMC complementary and alternative medicine · 2017Trial
- Comparative Effectiveness of Tai Chi Versus Physical Therapy for Knee Osteoarthritis: A Randomized Trial.Annals of internal medicine · 2016Trial
- The effect of exercise on clinical pain: a systematic umbrella review and meta-meta-analysis.Pain reports · 2026Article
- Evidence-Based Perspectives on Complementary and Alternative Medicine in Cancer Treatment: Current Advances and Clinical Relevance.Journal of multidisciplinary healthcare · 2026Review
- Evidence map of Tai Chi interventions for older adults.Frontiers in public health · 2026Review
- An unsupervised online Tai Chi program for people with knee osteoarthritis ("My Joint Tai Chi"): Study protocol for the RETREAT randomised controlled trial.Osteoarthritis and cartilage open · 2024Article
- Development of a 12-Week Unsupervised Online Tai Chi Program for People With Hip and Knee Osteoarthritis: Mixed Methods Study.JMIR aging · 2024Article
- Optimal Tai Chi forms in knee osteoarthritis: An exploration from biomechanical rationale to pain reduction.Osteoarthritis and cartilage open · 2024Article
- Effects of Tai Chi exercise on pain, functional status, and quality of life in patients with osteoarthritis or inflammatory arthritis.Turkish journal of physical medicine and rehabilitation · 2024Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWhether Tai Chi benefits patients with osteoarthritis remains controversial. We performed a meta-analysis to assess the effectiveness of Tai Chi exercise for pain, stiffness, and physical function in patients with osteoarthritis.
methodsA computerized search of PubMed and Embase (up to Sept 2012) was performed to identify relevant studies. The outcome measures were pain, stiffness, and physical function. Two investigators identified eligible studies and extracted data independently. The quality of the included studies was assessed by the Jadad score. Standard mean differences (SMDs) and 95% confidence intervals (CIs) were calculated and pooled using a random effects model. The change in outcomes from baseline was compared to the minimum clinically important difference.
resultsA total of seven randomized controlled trials involving 348 patients with osteoarthritis met the inclusion criteria. The mean Jadad score was 3.6. The pooled SMD was -0.45 (95% CI -0.70--0.20, P = 0.0005) for pain, -0.31 (95% CI -0.60--0.02, P = 0.04) for stiffness, and -0.61 (95% CI -0.85--0.37, P<0.00001) for physical function. A change of 32.2-36.4% in the outcomes was greater than the minimum clinically important difference.
conclusionsTwelve-week Tai Chi is beneficial for improving arthritic symptoms and physical function in patients with osteoarthritis and should be included in rehabilitation programs. However, the evidence may be limited by potential biases; thus, larger scale randomized controlled trials are needed to confirm the current findings and investigate the long-term effects of Tai Chi.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.