Evidence map›Paper›PMID 23620367›Full record

ArticleEuropean radiology2013

Combination of one-view digital breast tomosynthesis with one-view digital mammography versus standard two-view digital mammography: per lesion analysis.

Gisella Gennaro, R Edward Hendrick, Alicia Toledano, Jean R Paquelet, Elisabetta Bezzon, Roberta Chersevani, Cosimo di Maggio, Manuela La Grassa, Luigi Pescarini, Ilaria Polico and 4 more

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in European radiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. ACR Appropriateness Criteria® Imaging After Mastectomy and Breast Reconstruction.Journal of the American College of Radiology : JACR · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 2 countries.

Gisella GennaroVeneto Institute of Oncology (IRCCS), via Gattamelata, 64, 35128, Padua, Italy. gisella.gennaro@ioveneto.it
R Edward Hendrick
Alicia Toledano
Jean R Paquelet
Elisabetta Bezzon
Roberta Chersevani
Cosimo di Maggio
Manuela La Grassa
Luigi Pescarini
Ilaria Polico
Alessandro Proietti
Enrica Baldan
Fabio Pomerri
Pier Carlo Muzzio
Istituti di Ricovero e Cura a Carattere Scientifico · ITIstituto Oncologico Veneto · ITBanner McKee Medical Center · USBiostatistical Consulting (United States) · USCentro di Riferimento Oncologico · ITIstituto di Sociologia Internazionale di Gorizia · ITUniversity of Colorado Denver · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the clinical value of combining one-view mammography (cranio-caudal, CC) with the complementary view tomosynthesis (mediolateral-oblique, MLO) in comparison to standard two-view mammography (MX) in terms of both lesion detection and characterization.

methodsA free-response receiver operating characteristic (FROC) experiment was conducted independently by six breast radiologists, obtaining data from 463 breasts of 250 patients. Differences in mean lesion detection fraction (LDF) and mean lesion characterization fraction (LCF) were analysed by analysis of variance (ANOVA) to compare clinical performance of the combination of techniques to standard two-view digital mammography.

resultsThe 463 cases (breasts) reviewed included 258 with one to three lesions each, and 205 with no lesions. The 258 cases with lesions included 77 cancers in 68 breasts and 271 benign lesions to give a total of 348 proven lesions. The combination, DBT(MLO)+MX(CC), was superior to MX (CC+MLO) in both lesion detection (LDF) and lesion characterization (LCF) overall and for benign lesions. DBT(MLO)+MX(CC) was non-inferior to two-view MX for malignant lesions.

conclusionsThis study shows that readers' capabilities in detecting and characterizing breast lesions are improved by combining single-view digital breast tomosynthesis and single-view mammography compared to two-view digital mammography. KEY POINTS: • Digital breast tomosynthesis is becoming adopted as an adjunct to mammography (MX) • DBT (MLO) +MX (CC) is superior to MX (CC+MLO) in lesion detection (overall and benign lesions) • DBT (MLO) +MX (CC) is non-inferior to MX (CC+MLO) in cancer detection • DBT (MLO) +MX (CC) is superior to MX (CC+MLO) in lesion characterization (overall and benign lesions) • DBT (MLO) +MX (CC) is non-inferior to MX (CC+MLO) in characterization of malignant lesions.

Indexed as

AdultAgedAged, 80 and overBreastBreast NeoplasmsFalse Positive ReactionsFemaleHumansImaging, Three-DimensionalMammographyMiddle AgedMultimodal ImagingObserver VariationRadiographic Image EnhancementRadiographic Image Interpretation, Computer-AssistedReproducibility of Results

Identifiers

PMID23620367
OpenAlexW2129563666

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.