Evidence map›Paper›PMID 23620158›Full record

ArticlePathogens and disease2013

Bordetella holmesii: initial genomic analysis of an emerging opportunist.

Paul J Planet, Apurva Narechania, Saul R Hymes, Christina Gagliardo, Richard C Huard, Susan Whittier, Phyllis Della-Latta, Adam J Ratner

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Pathogens and disease, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Paul J PlanetDepartment of Pediatrics, Columbia University, New York, NY, USA.
Apurva Narechania
Saul R Hymes
Christina Gagliardo
Richard C Huard
Susan Whittier
Phyllis Della-Latta
Adam J Ratner
Columbia University · USNewYork–Presbyterian Hospital · USAmerican Museum of Natural History · US

Funding

Training in Pediatric Infectious DiseasesT32AI007531 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI PRINCE, ALICE S, SAIMAN, LISA · 1998 to 2023
$4.0M
Gardnerella vaginalis: toxin production and pathogenesisR01AI092743 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI RATNER, ADAM JONATHAN · 2011 to 2015
$2.0M
DNase For Prevention Of Reproductive Tract Infections In PregnancyR21AI098654 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI RATNER, ADAM JONATHAN · 2012 to 2013
$448k
Role of Staphylococcus aureus SpA in Microbial Competition and Host ColonizationK08AI101005 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI PLANET, PAUL J · 2012 to 2014
$405k
NIAID NIH HHS K08 AI101005NIAID NIH HHS R01 AI092743NIAID NIH HHS R21 AI098654NIAID NIH HHS T32 AI007531NIAID NIH HHS T32-AI007531
6 · The paper itself

Abstract

Bordetella holmesii is an emerging opportunistic pathogen that causes respiratory disease in healthy individuals and invasive infections among patients lacking splenic function. We used 16S rRNA gene analysis to confirm B. holmesii as the cause of bacteremia in a child with sickle cell disease. Semiconductor-based draft genome sequencing provided insight into B. holmesii phylogeny and potential virulence mechanisms and also identified a toluene-4-monoxygenase locus unique among bordetellae.

Indexed as

Genome, BacterialAnemia, Sickle CellBacteremiaBordetellaBordetella InfectionsChildFemaleGenomicsHumansOpportunistic InfectionsOxygenasesPhylogenyRNA, Ribosomal, 16SSequence Analysis, DNAOxygenasesRNA, Ribosomal, 16Stoluene-4-monooxygenase

Identifiers

PMID23620158
PMCPMC3653170
OpenAlexW1972870030

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.