ReviewJournal of leukocyte biology2013
Cross-talk between intraepithelial γδ T cells and epithelial cells.
Review in Journal of leukocyte biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 30 citations in OpenAlex.
- Immune cell dynamics and mechanisms of epithelial injury in celiac disease.Frontiers in immunology · 2026Review
- Imperfect wound healing sets the stage for chronic diseases.Science (New York, N.Y.) · 2024Review
- Porcine intraepithelial lymphocytes undergo migration and produce an antiviral response following intestinal virus infection.Communications biology · 2022Article
- Regulation of Enteric Infection and Immunity by Dietary Proanthocyanidins.Frontiers in immunology · 2021Review
- Perforins Expression by Cutaneous Gamma Delta T Cells.Frontiers in immunology · 2020Review
- A polyphenol-enriched diet and Ascaris suum infection modulate mucosal immune responses and gut microbiota composition in pigs.PloS one · 2017Article
- The composition of T cell subtypes in duodenal biopsies are altered in coeliac disease patients.PloS one · 2017Article
- IL-12 protects from psoriasiform skin inflammation.Nature communications · 2016Article
- CD8αα TCRαβ Intraepithelial Lymphocytes in the Mouse Gut.Digestive diseases and sciences · 2016Review
- Dendritic epidermal T cells facilitate wound healing in diabetic mice.American journal of translational research · 2016Article
- Cellular Barriers after Extravasation: Leukocyte Interactions with Polarized Epithelia in the Inflamed Tissue.Mediators of inflammation · 2016Review
- Enhanced differentiation of intraepithelial lymphocytes in the intestine of polymeric immunoglobulin receptor-deficient mice.Immunology · 2015Article
- Dedicated immunosensing of the mouse intestinal epithelium facilitated by a pair of genetically coupled lectin-like receptors.Mucosal immunology · 2015Article
- Primary γδ T cell lymphoma of the lung: report of a case with features suggesting derivation from intraepithelial γδ T lymphocytes.Virchows Archiv : an international journal of pathology · 2014Article
- The mucus and mucins of the goblet cells and enterocytes provide the first defense line of the gastrointestinal tract and interact with the immune system.Immunological reviews · 2014Review
- Mechanisms regulating skin immunity and inflammation.Nature reviews. Immunology · 2014Review
- Immunology: oiling the wheels of autoimmunity.Nature · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Intraepithelial γδ T cells play pivotal roles in homeostasis, tissue repair, inflammation, and protection from malignancy. In some tissues, γδ T cells are the only resident T cell population, whereas in others, they coexist with αβ T cells and other lymphocyte populations. γδ T cell function in the epithelium requires constant communication between cells in the form of cell-to-cell contacts and cell-to-matrix interactions. These interactions coordinate with the timely production of specific cytokines, chemokines, growth factors, and glycosaminoglycans, which have specialized effects on neighboring epithelial cells. Antigens that activate these T cells are not well-defined, and they do not express classic costimulatory or coreceptor molecules. As such, an understanding of the mechanisms used by epithelial γδ T cells to maintain homeostasis and facilitate wound repair has necessitated the identification of novel molecular interactions between γδ T cells and their neighboring epithelial cells.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.