Evidence map›Paper›PMID 23619984›Full record

ArticleHeart (British Cardiac Society)2013

Chronic exposure to biomass fuel is associated with increased carotid artery intima-media thickness and a higher prevalence of atherosclerotic plaque.

Matthew S Painschab, Victor G Davila-Roman, Robert H Gilman, Angel D Vasquez-Villar, Suzanne L Pollard, Robert A Wise, J Jaime Miranda, William Checkley, CRONICAS Cohort Study Group

Open access · greenAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Heart (British Cardiac Society), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 6 pooled it
7.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 6 syntheses or guidelines pooled it, 102 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Matthew S PainschabSchool of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA.
Victor G Davila-Roman
Robert H Gilman
Angel D Vasquez-Villar
Suzanne L Pollard
Robert A Wise
J Jaime Miranda
William Checkley
CRONICAS Cohort Study Group
Johns Hopkins Medicine · USJohns Hopkins University · USHospital Base Guillermo Almenara Irigoyen · PEUniversidad Peruana Cayetano Heredia · PEWashington University in St. Louis · US

Funding

Fogarty International Clinical Research Scholars Support Center @ Vanderbilt-AAMCR24TW007988 · FIC · VANDERBILT UNIVERSITY · PI VERMUND, STEN H. · 2007 to 2011
$27.6M
Acute Lung Injury: Application of Novel Approaches to Longitudinal Data AnalysisR00HL096955 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI CHECKLEY, WILLIAM · 2011 to 2013
$723k
Acute Lung Injury: Application of Novel Approaches to Longitudinal Data AnalysisK99HL096955 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI CHECKLEY, WILLIAM · 2009 to 2010
$269k
FIC NIH HHS R24 TW007988FIC NIH HHS R24TW007988Medical Research Council MR/K007467/1NHLBI NIH HHS HHSN268200900033CNHLBI NIH HHS K99 HL096955NHLBI NIH HHS R00 HL096955NHLBI NIH HHS R00HL096955Wellcome Trust 084674Wellcome Trust 098504
6 · The paper itself

Abstract

backgroundBiomass fuels are used for cooking in the majority of rural households worldwide. While their use is associated with an increased risk of lung diseases and all-cause mortality, the effects on cardiovascular disease (CVD) are not well characterised. Exposure to biomass fuel smoke has been associated with lung-mediated inflammation and oxidative stress, which may increase the risk of atherosclerosis as evaluated by carotid intima-media thickness (CIMT), carotid atherosclerotic plaque prevalence and blood pressure.

methodsA cross-sectional study was performed in 266 adults aged ≥35 years in Puno, Peru (3825 m above sea level). We stratified participants by their long-term history of exposure to clean fuel (n=112) or biomass fuel (n=154) and measured 24 h indoor particulate matter (PM2.5) in a random subset (n=84). Participants completed questionnaires and underwent a clinical assessment, laboratory analyses and carotid artery ultrasound. The main outcome measures were CIMT, carotid plaque and blood pressure.

resultsThe groups were similar in age and gender. The biomass fuel group had greater unadjusted mean CIMT (0.66 vs 0.60 mm; p<0.001), carotid plaque prevalence (26% vs 14%; p=0.03), systolic blood pressure (118 vs 111 mm Hg; p<0.001) and median household PM2.5 (280 vs 14 µg/m(3); p<0.001). In multivariable regression, the biomass fuel group had greater mean CIMT (mean difference=0.03 mm, 95% CI 0.01 to 0.06; p=0.02), a higher prevalence of carotid plaques (OR=2.6, 95% CI 1.1 to 6.0; p=0.03) and higher systolic blood pressure (mean difference=9.2 mm Hg, 95% CI 5.4 to 13.0; p<0.001).

conclusionsChronic exposure to biomass fuel was associated with increased CIMT, increased prevalence of atherosclerotic plaques and higher blood pressure. These findings identify biomass fuel use as a risk factor for CVD, which may have important global health implications.

Indexed as

Carotid Intima-Media ThicknessCookingAdultAgedCardiovascular DiseasesCross-Sectional StudiesDisease ProgressionFemaleFollow-Up StudiesHumansMaleMiddle AgedOilsPeruPlaque, AtheroscleroticPrevalenceOils

Identifiers

PMID23619984
PMCPMC4657551
OpenAlexW2122235906

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.