Evidence map›Paper›PMID 23619953›Full record

Trial reportJournal of autism and developmental disorders2013

Cognitive enhancement therapy for adults with autism spectrum disorder: results of an 18-month feasibility study.

Shaun M Eack, Deborah P Greenwald, Susan S Hogarty, Amber L Bahorik, Maralee Y Litschge, Carla A Mazefsky, Nancy J Minshew

Registry-linked trialOpen access · greenAbstract readClinical Trial
In one paragraph

Trial report in Journal of autism and developmental disorders, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03432832 (Emotion Awareness and Skills Enhancement), which is not on this map. Cited by 36 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 2 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03432832 nacompletednot on this mapstarted 2018, after this paper: background citation

Emotion Awareness and Skills Enhancement (EASE) Program: A Clinical Trial

TypeinterventionalSponsorUniversity of PittsburghRan2018 to 2024Enrolled113ConditionsAutism Spectrum DisorderArmsEASE, Supportive Therapy
3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 2 syntheses or guidelines pooled it, 81 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Cognitive enhancement therapy for adult autism spectrum disorder: Results of an 18-month randomized clinical trial.Autism research : official journal of the International Society for Autism Research · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Shaun M EackSchool of Social Work, University of Pittsburgh, 2117 Cathedral of Learning, Pittsburgh, PA, 15260, USA, sme12@pitt.edu.
Deborah P Greenwald
Susan S Hogarty
Amber L Bahorik
Maralee Y Litschge
Carla A Mazefsky
Nancy J Minshew
University of Pittsburgh · USUniversity of Pittsburgh Medical Center · US

Funding

University of Pittsburgh Clinical and Translational Science InstitutionKL2RR024154 · NCRR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2006 to 2011
$22.2M
SYSTEMS CONNECTIVITY + BRAIN ACTIVATION:IMAGING STUDIES OF LANGUAGE + PERCEPTIONP50HD055748 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CONTURO, THOMAS EDWARD · 2007 to 2011
$9.7M
University of Pittsburgh Clinical and Translational Science InstitutionKL2TR000146 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2012 to 2015
$8.7M
Social-Cognitive Rehabilitation and Brain Function in Early SchizophreniaK23MH095783 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI EACK, SHAUN M · 2012 to 2015
$629k
Adapting Cognitive Enhancement Therapy for ASDR33MH085851 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MINSHEW, NANCY J · 2011 to 2013
$624k
Cognitive Control of Emotion in AutismK23HD060601 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MAZEFSKY, CARLA A · 2010 to 2014
$510k
Adapting Cognitive Enhancement Therapy for ASDR21MH085851 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MINSHEW, NANCY J · 2009 to 2010
$400k
Autism Speaks AS5703NCATS NIH HHS KL2 TR000146NCRR NIH HHS K12 RR024154NCRR NIH HHS KL2 RR024154NCRR NIH HHS RR-24154NICHD NIH HHS HD-55748NICHD NIH HHS K23 HD060601NICHD NIH HHS P50 HD055748NIMH NIH HHS K23 MH095783NIMH NIH HHS MH-85851NIMH NIH HHS MH-95783NIMH NIH HHS R21 MH085851NIMH NIH HHS R33 MH085851
6 · The paper itself

Abstract

Adults with autism experience significant impairments in social and non-social information processing for which few treatments have been developed. This study conducted an 18-month uncontrolled trial of Cognitive Enhancement Therapy (CET), a comprehensive cognitive rehabilitation intervention, in 14 verbal adults with autism spectrum disorder to investigate its feasibility, acceptability, and initial efficacy in treating these impairments. Results indicated that CET was satisfying to participants, with high treatment attendance and retention. Effects on cognitive deficits and social behavior were also large (d = 1.40-2.29) and statistically significant (all p < .001). These findings suggest that CET is a feasible, acceptable, and potentially effective intervention for remediating the social and non-social cognitive impairments in verbal adults with autism.

Indexed as

AdolescentAdultChild Development Disorders, PervasiveCognitive Behavioral TherapyFeasibility StudiesFemaleHumansMaleMiddle AgedNeuropsychological TestsSocial BehaviorYoung Adult

Identifiers

PMID23619953
PMCPMC3773526
OpenAlexW2087957961

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.