ArticleInternational journal of colorectal disease2013
Risk factors for vertical incomplete resection in endoscopic submucosal dissection as total excisional biopsy for submucosal invasive colorectal carcinoma.
Article in International journal of colorectal disease, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Article
- Efficacy of Hybrid Endoscopic Submucosal Dissection to Ensure Adequate Submucosal Layer for T1b Colorectal Carcinomas of 20-30 mm in Diameter.Journal of the anus, rectum and colon · 2025Article
- Vertical margin distance in T1 colorectal carcinoma resected by endoscopic submucosal dissection affects prognosis after additional surgery.International journal of colorectal disease · 2024Article
- Clinical significance of immunohistochemical lymphovascular evaluation to determine additional surgery after endoscopic submucosal dissection for colorectal T1 carcinoma.International journal of colorectal disease · 2021Article
- Preceding endoscopic submucosal dissection for T1 colorectal carcinoma does not affect the prognosis of patients who underwent additional surgery: a large multicenter propensity score-matched analysis.Journal of gastroenterology · 2019Article
- Additional surgery after endoscopic submucosal dissection for colorectal cancer: a review of 53 cases.International journal of colorectal disease · 2019Review
- Preoperative endoscopic predictors of severe submucosal fibrosis in colorectal tumors undergoing endoscopic submucosal dissection.Endoscopy international open · 2019Article
- Cost Analysis of Endoscopic Submucosal Dissection for the Treatment of Colorectal Lesions in China.BioMed research international · 2019Article
- Clinicopathological features of T1 colorectal carcinomas with skip lymphovascular invasion.Oncology letters · 2018Article
- Long-term outcomes after treatment for T1 colorectal carcinoma: a multicenter retrospective cohort study of Hiroshima GI Endoscopy Research Group.Journal of gastroenterology · 2017Article
- Review
- Long-term outcomes after treatment for T1 colorectal carcinoma.International journal of colorectal disease · 2016Article
- Colorectal Endoscopic Submucosal Dissection: Past, Present, and Factors Impacting Future Dissemination.Clinics in colon and rectal surgery · 2015Review
- Risk factors for delayed bleeding after endoscopic submucosal dissection for colorectal neoplasms.International journal of colorectal disease · 2014Article
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Authors and funding
10 authors.
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Abstract
purposeEndoscopic submucosal dissection (ESD) for colorectal tumor is a minimally invasive treatment. Histologic information obtained from the entire ESD specimen is important for therapy selection in submucosal invasive colorectal carcinoma (SMca). This study aimed to identify risk factors for vertical incomplete resection (vertical margin-positive [VM+]) when ESD was performed as total excisional biopsy for SMca.
methodsFrom June 2003 through December 2011, 78 SMca cases were resected by ESD at Hiroshima University Hospital. Patient and tumor characteristics, intraoperative variables, and histopathology were compared between the VM+ group and the vertical complete resection (vertical margin-negative) group. The ability of magnifying endoscopy (ME) and endoscopic ultrasonography (EUS) to predict VM+ was assessed.
resultsESD resulted in VM+ in eight cases (10.3 %), with a greater percentage invading to a depth of ≥2,000 vs. <2,000 μm (P = 0.047). Severe submucosal fibrosis was found in five of the eight cases (62.5 %, P = 0.017). Poor differentiation was seen at the deepest invasive portion in six cases (75.0 %), and two of six cases had an invasion depth <2,000 μm. Of 39 EUS cases, 36 not showing deep invasion close to the muscularis propria were completely resected by ESD.
conclusionsSubmucosal fibrosis and poor differentiation at the deepest invasive portion may be risk factors for VM+ in colorectal ESD for tumors with submucosal deep invasion. ME plus EUS is more likely to help determine whether ESD is indicated as complete total excisional biopsy for SMca.
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