Evidence map›Paper›PMID 23619597›Full record

ReviewCurrent allergy and asthma reports2013

Obesity in asthma: approaches to treatment.

Shyamala Pradeepan, Garth Garrison, Anne E Dixon

Abstract readReview
In one paragraph

Review in Current allergy and asthma reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Airway Smooth Muscles Contractions in Metabolic Syndrome.Bulletin of experimental biology and medicine · 2022
    Article
  8. Therapeutic ketosis decreases methacholine hyperresponsiveness in mouse models of inherent obese asthma.American journal of physiology. Lung cellular and molecular physiology · 2022
    Article
  9. An Overview of the Obese-Asthma Phenotype in Children.International journal of environmental research and public health · 2022
    Review
  10. Article
  11. Article
  12. Article
  13. Asthma Phenotypes as a Guide for Current and Future Biologic Therapies.Clinical reviews in allergy & immunology · 2020
    Review
  14. Diabetic lung disease: fact or fiction?Reviews in endocrine & metabolic disorders · 2019
    Review
  15. Obesity and severe asthma.Allergology international : official journal of the Japanese Society of Allergology · 2019
    Review
  16. Review
  17. Overweight adolescents and asthma: Revealing motivations and challenges with adolescent-provider communication.The Journal of asthma : official journal of the Association for the Care of Asthma · 2018
    Article
  18. Omalizumab for Severe Asthma: Beyond Allergic Asthma.BioMed research international · 2018
    Review
  19. Pathophysiology to Phenotype in the Asthma of Obesity.Annals of the American Thoracic Society · 2017
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Shyamala PradeepanDepartment of Respiratory and Sleep Medicine, John Hunter Hospital Newcastle, Lookout Road, New Lambton, NSW, 2305, Australia, shyamala.pradeepan@hnehealth.nsw.gov.au.
Garth Garrison
Anne E Dixon
University of Vermont · USJohn Hunter Hospital · AU

Funding

WEIGHT LOSS & ASTHMAP20RR015557 · NCRR · UNIVERSITY OF VERMONT &ST AGRIC COLLEGE · PI IRVIN, CHARLES G · 2000 to 2009
$21.4M
NCRR NIH HHS P20 RR015557
6 · The paper itself

Abstract

There is mounting evidence that obesity is associated with asthma, both of which are seeing a dramatic increase in prevalence. Not only is obesity a risk factor for the development of asthma but it is also associated with poor asthma control. Asthma phenotypes associated with obesity include early-onset allergic asthma and late-onset non-allergic asthma. The pathogenesis of the linkage is complex; obesity causes a variety of mechanical, metabolic, and immunological changes that can affect the airways. The treatment of asthma in obesity can be challenging, as obesity is associated with poor response to standard controller medications. A tailored approach that involves combining pharmacologic and non-pharmacologic therapies including weight loss, dietary interventions, and exercise, along with identification and treatment of obstructive sleep apnea, should therefore be considered in this population.

Indexed as

AnimalsAsthmaExercise TherapyHumansObesityPrevalenceRisk FactorsSleep Apnea, Obstructive

Identifiers

PMID23619597
PMCPMC3778029
OpenAlexW1975200488

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.