Evidence map›Paper›PMID 23619508›Full record

ReviewPediatric nephrology (Berlin, Germany)2014

The bioartificial kidney: current status and future promise.

H David Humes, Deborah Buffington, Angela J Westover, Shuvo Roy, William H Fissell

Abstract readReview
PubMed Publisher
In one paragraph

Review in Pediatric nephrology (Berlin, Germany), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Artificial kidney: Challenges and opportunities.World journal of transplantation · 2024
    Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Approaches to kidney replacement therapies-opportunities and challenges.Frontiers in cell and developmental biology · 2022
    Review
  12. Powering Implantable and Ingestible Electronics.Advanced functional materials · 2021
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Remote sensing and signaling in kidney proximal tubules stimulates gut microbiome-derived organic anion secretion.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

H David HumesInnovative BioTherapies, Inc., 650 Avis Dr., Suite 300, Ann Arbor, MI, 48108, USA, dhumes@med.umich.edu.
Deborah Buffington
Angela J Westover
Shuvo Roy
William H Fissell

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rapid understanding of the cellular and molecular bases of organ function and disease processes will be translated in the next decade into new therapeutic approaches to a wide range of clinical disorders, including acute and chronic renal failure. Central to these new therapies are the developing technologies of cell therapy and tissue engineering, which are based on the ability to expand stem or progenitor cells in tissue culture to perform differentiated tasks and to introduce these cells into the patient either via extracorporeal circuits or as implantable constructs. Cell therapy devices are currently being developed to replace the filtrative, metabolic, and endocrinologic functions of the kidney lost in both acute and chronic renal failure. This review summarizes the current state of development of a wearable or implantable bioartificial kidney. These devices have the promise to be combined to produce a wearable or implantable bioartificial kidney for full renal replacement therapy that may significantly diminish morbidity and mortality in patients with acute or chronic kidney disease.

Indexed as

Bioartificial OrgansKidneyKidneys, ArtificialStem Cell TransplantationAnimalsCells, CulturedDisease Models, AnimalEquipment DesignForecastingHumansKidney DiseasesRenal Replacement TherapyTissue EngineeringTissue ScaffoldsTreatment Outcome

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.