Evidence map›Paper›PMID 23618210›Full record

SynthesisCanadian journal of public health = Revue canadienne de sante publique2013

Self-collected HPV testing improves participation in cervical cancer screening: a systematic review and meta-analysis.

C Sarai Racey, Diana R Withrow, Dionne Gesink

Registry-linked trialAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC
In one paragraph

Synthesis in Canadian journal of public health = Revue canadienne de sante publique, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03139669 (Cultural Acceptability and Feasibility of HPV Cervical Self Collection Aided by Lay Navigators), which is not on this map. Cited by 131 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
131citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03139669 nacompletednot on this mapstarted 2016, after this paper: background citation

Cultural Acceptability and Feasibility of HPV Cervical Self Collection Aided by Lay Navigators

TypeinterventionalSponsorUniversity of VirginiaRan2016 to 2019Enrolled45ConditionsHuman Papilloma VirusArmsViba collection brush
3 · Its place in the literature

Who cites it

131 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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  10. Performance and acceptability of self-collected human papillomavirus testing among women living with HIV.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2020
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71 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

C Sarai RaceyDalla Lana School of Public Health, University of Toronto, Toronto, ON. sarai.racey@gmail.com
Diana R Withrow
Dionne Gesink

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveHPV testing has emerged as an effective cervical cancer screening test. The use of HPV self-testing has the potential to address many barriers to screening and reach at-risk women through engagement in screening. However, there is a need to examine the evidence for whether offering self-collected HPV testing in practice increases screening compliance. The objective of this review is to determine to what extent providing self-collected HPV testing increases screening participation in women who are never or underscreened for cervical cancer.

methodsA systematic literature review conducted in the databases Medline and Embase identified articles examining the use of HPV self-testing on cervical cancer screening participation. A meta-analysis using a random-effects model was used to calculate the relative compliance, with an intent-to-treat analysis of HPV self-testing compared to Pap testing, with 95% confidence intervals (CI). All statistical tests were two-sided. SYNTHESIS: Ten studies were reviewed, with 8 being European and 2 North American. Of the 10 studies, 9 employed a randomized design. In all studies, the relative compliance of HPV self-collected testing compared to Pap testing was significantly greater than 1.0 (p<0.01). The overall relative compliance was 2.14 (95% CI 1.30-3.52). There was large heterogeneity of screening compliance between studies for both HPV self-testing and Pap testing.

conclusionHPV self-collected testing significantly improved the participation of women who did not routinely attend cervical cancer screening programs. New approaches to HPV self-test delivery should be considered as HPV testing becomes more widely incorporated as a primary screening tool.

Indexed as

Early Detection of CancerFemaleHumansPapillomavirus InfectionsPatient ParticipationRandomized Controlled Trials as TopicSelf CareSpecimen HandlingUterine Cervical Neoplasmscervical cancer screeningHuman papillomavirusreviewself collected specimensunder-screening

Identifiers

PMID23618210
PMCPMC6973997

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.