Evidence map›Paper›PMID 23617864›Full record

Trial reportThe American journal on addictions

Cognitive behavioral therapy and the nicotine transdermal patch for dual nicotine and cannabis dependence: a pilot study.

Kevin P Hill, Lindsay H Toto, Scott E Lukas, Roger D Weiss, George H Trksak, John M Rodolico, Shelly F Greenfield

Abstract readClinical Trial
In one paragraph

Trial report in The American journal on addictions. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. A scoping review and meta-analysis of psychosocial and pharmacological treatments for cannabis and tobacco use among African Americans.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2017
    Pooled it
  2. Psychosocial interventions for cannabis use disorder.The Cochrane database of systematic reviews · 2016
    Pooled it
  3. Cannabis and Alcohol Co-Use in a Smoking Cessation Pharmacotherapy Trial for Adolescents and Emerging Adults.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2020
    Trial
  4. Trial
  5. Trial
  6. Trial
  7. Review
  8. Article
  9. Article
  10. Nicotine and Opioids: a Call for Co-treatment as the Standard of Care.The journal of behavioral health services & research · 2020
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kevin P HillDivision of Alcohol and Drug Abuse, McLean Hospital, Belmont, Massachusetts, USA. khill@mclean.harvard.edu
Lindsay H Toto
Scott E Lukas
Roger D Weiss
George H Trksak
John M Rodolico
Shelly F Greenfield

Funding

Mentoring in Substance Abuse Treatment ResearchK24DA019855 · NIDA · MC LEAN HOSPITAL (BELMONT, MA) · PI GREENFIELD, SHELLY F. · 2005 to 2014
$1.8M
Mentoring in Drug Abuse and Dual Diagnosis ResearchK24DA022288 · NIDA · MCLEAN HOSPITAL · PI WEISS, ROGER D. · 2007 to 2016
$1.8M
Nabilone for Cannabis Dependence: Imaging and Neuropsychological PerformanceR00DA029115 · NIDA · MCLEAN HOSPITAL · PI HILL, KEVIN P. · 2013 to 2015
$819k
Nabilone for Cannabis Dependence: Imaging and Neuropsychological PerformanceK99DA029115 · NIDA · MCLEAN HOSPITAL · PI HILL, KEVIN P. · 2011 to 2012
$359k
NIDA NIH HHS K24 DA019855NIDA NIH HHS K24 DA022288NIDA NIH HHS K99 DA029115NIDA NIH HHS K99/R00 DA029115NIDA NIH HHS R00 DA029115
6 · The paper itself

Abstract

BACKGROUND AND

objectivesWe assessed the feasibility of a new cognitive behavioral therapy (CBT) manual, plus transdermal patch nicotine replacement therapy (NRT), to treat co-occurring nicotine and cannabis dependence.

methodSeven of 12 (58.3%) adults with DSM-IV diagnoses of both nicotine and cannabis dependence completed 10 weeks of individual CBT and NRT.

resultsParticipants smoked 12.6 ± 4.9 tobacco cigarettes per day at baseline, which was reduced to 2.1 ± 4.2 at the end of treatment (F[5]  = 23.5, p < .0001). The reduction in cannabis use from 10.0 ± 5.3 inhalations per day at baseline to 8.0 ± 5.3 inhalations per day at 10 weeks was not significant (F[5]  = 1.12, p = .37). There was a significant decrease from the mean baseline Fagerstrom Test for Nicotine Dependence scores at weeks 4, 6, 8, and 10 of treatment (F[4]  = 19.8, p < .001) and mean Client Satisfaction Questionnaire scores were uniformly high (30.6 ± 1.9). CONCLUSIONS AND SCIENTIFIC SIGNIFICANCE: A CBT plus NRT treatment program significantly reduced tobacco smoking but did not significantly reduce cannabis use in individuals with co-occurring nicotine and cannabis dependence. There was no compensatory increase in cannabis use following the reduction in tobacco smoking, suggesting that clinicians can safely pursue simultaneous treatment of co-occurring nicotine and cannabis dependence. The intervention was well-liked by the 7 of the 12 enrollees who completed the study.

Indexed as

Tobacco Use Cessation DevicesAdministration, CutaneousAdultAnalysis of VarianceCarbon MonoxideCognitive Behavioral TherapyCombined Modality TherapyCotinineDronabinolFeasibility StudiesFemaleHumansMaleMarijuana AbuseNicotinePilot ProjectsCarbon MonoxideCotinineDronabinolNicotine

Identifiers

PMID23617864
PMCPMC3641687

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.