ArticleJournal of the American Geriatrics Society2013
Effects of depression diagnosis and antidepressant treatment on mortality in Medicare beneficiaries with chronic obstructive pulmonary disease.
Article in Journal of the American Geriatrics Society, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- All-cause and cause-specific mortality in people with depression: a large-scale systematic review and meta-analysis of relative risk and aggravating or attenuating factors, including antidepressant treatment.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2025Article
- The association of antidepressant treatment with COPD maintenance medication use and adherence in a comorbid Medicare population: A longitudinal cohort study.International journal of geriatric psychiatry · 2018Article
- Adherence and healthcare utilization among older adults with COPD and depression.Respiratory medicine · 2017Article
- Depression treatment patterns among adults with chronic obstructive pulmonary disease and depression.Current medical research and opinion · 2017Article
- Adherence to Maintenance Medications among Older Adults with Chronic Obstructive Pulmonary Disease. The Role of Depression.Annals of the American Thoracic Society · 2016Article
- New episodes of depression among Medicare beneficiaries with chronic obstructive pulmonary disease.International journal of geriatric psychiatry · 2016Article
- Association of Psychological Disorders With 30-Day Readmission Rates in Patients With COPD.Chest · 2016Article
- Patterns of Depression Treatment in Medicare Beneficiaries with Depression after Traumatic Brain Injury.Journal of neurotrauma · 2015Article
- Comorbidities and Chronic Obstructive Pulmonary Disease: Prevalence, Influence on Outcomes, and Management.Seminars in respiratory and critical care medicine · 2015Review
- Managing comorbidities in COPD.International journal of chronic obstructive pulmonary disease · 2015Review
- Depression and risk of hospitalization for pneumonia in a cohort study of older Americans.Journal of psychosomatic research · 2014Article
- Pharmacological treatment of depression in older patients with chronic obstructive pulmonary disease: impact on the course of the disease and health outcomes.Drugs & aging · 2014Review
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
objectivesTo estimate the effects of depression diagnosis and antidepressant treatment on 2-year all-cause mortality in Medicare beneficiaries with chronic obstructive pulmonary disease (COPD) and determine whether Social Security Disability Insurance (SSDI) eligibility modifies these relationships.
designRetrospective cohort study.
settingA 5% random sample of Medicare beneficiaries aged 65 and older in stand-alone Part D plans in 2006 to 2008.
participantsBeneficiaries diagnosed with COPD and continuously enrolled in Medicare Parts A, B, and D (N = 75,699). MEASUREMENTS: Depression diagnosis was assessed at baseline (2006). Evidence of antidepressant treatment was measured across time. Covariates included baseline characteristics, comorbidities, and disease severity. Survival analyses using Cox proportional hazards models estimated 2-year mortality associated with depression diagnosis or antidepressant treatment (in beneficiaries with depression). Interaction terms of SSDI eligibility with baseline depression and time-dependent antidepressant treatment were tested.
resultsMore than one-fifth (21.6%) of beneficiaries with COPD had a depression diagnosis at baseline, and 82.1% of those received antidepressants. Nearly one-sixth (16.3%) of the sample were SSDI eligible. Baseline depression heightened risk of death (hazard ratio = 1.13, 95% confidence interval = 1.09-1.18) in beneficiaries who were not eligible for SSDI. In beneficiaries with depression, the association between antidepressant treatment and lower mortality was different according to SSDI eligibility status.
conclusionSocial Security Disability Insurance eligibility modifies the effects of depression and antidepressant treatment on mortality in Medicare beneficiaries with COPD. These data suggest that clinicians should identify and treat depression in individuals with COPD, but further studies are needed to determine the effect of these interventions.
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