ArticleBMC genomics2013
Comparative analysis of fungal genomes reveals different plant cell wall degrading capacity in fungi.
Article in BMC genomics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 289 papers, 1 of them a synthesis that pooled it.
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Who cites it
289 citing papers in PubMed, 1 synthesis or guideline pooled it, 702 citations in OpenAlex.
- Priority actions for Fusarium head blight resistance in durum wheat: Insights from the wheat initiative.The plant genome · 2025Pooled it
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- Genomes of the ex-type strains of Elsinoë mangiferae and E. perseae, the causal agents of scab on mango and avocado.G3 (Bethesda, Md.) · 2026Article
- Eukaryotic metagenome-assembled genomes recovered from deep metagenomic sequencing of the seagrass,Microbial genomics · 2026Article
- A Fungal Glycoside Hydrolase From Colletotrichum asianum Mini-Chromosomes Targets Host Chitinase to Suppress Plant Immunity.Molecular plant pathology · 2026Article
- Genome Assembly and Genomic Characterization ofJournal of fungi (Basel, Switzerland) · 2026Article
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- Genome-Wide Characterization of thePlants (Basel, Switzerland) · 2026Article
- Transcriptome study ofMicrobiology spectrum · 2026Article
- MultifunctionalJournal of fungi (Basel, Switzerland) · 2026Article
- The Maximum Growth Temperature for Eukaryotes Is Thermodynamically Driven but Ecologically Contingent.Life (Basel, Switzerland) · 2026Article
- Genomic and Metabolomic Comparisons Provide New Insights into Plant Cell Wall Degradation, Mating Diversity and Secondary Metabolites in Brown and White CommercialInternational journal of molecular sciences · 2026Article
- The deletion of a major facilitator superfamily geneMicrobiology spectrum · 2026Article
- Occupancy as a key attribute linking saprotrophic fungi to soil carbon decomposition.National science review · 2026Article
- Genomic Basis of Lifestyle Divergence in Rice-AssociatedInternational journal of molecular sciences · 2026Article
- Integrated taxonomy and genomic analysis of Marssonina zanthoxyli, the causal agent of prickly ash leaf defoliation.BMC genomics · 2026Article
- Genome-wide prediction of secretory proteins in Ceratocystis paradoxa and expression analysis of effectors during early infection.BMC microbiology · 2026Article
- Comparative genomics of Fusarium oxysporum f. sp. albedinis reveals the effector repertoire and molecular arsenal for date palm infection.BMC plant biology · 2026Article
- Comparative analysis towards the identification of genome wide characteristics of a beneficial fungal endophyte.Scientific reports · 2026Article
229 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFungi produce a variety of carbohydrate activity enzymes (CAZymes) for the degradation of plant polysaccharide materials to facilitate infection and/or gain nutrition. Identifying and comparing CAZymes from fungi with different nutritional modes or infection mechanisms may provide information for better understanding of their life styles and infection models. To date, over hundreds of fungal genomes are publicly available. However, a systematic comparative analysis of fungal CAZymes across the entire fungal kingdom has not been reported.
resultsIn this study, we systemically identified glycoside hydrolases (GHs), polysaccharide lyases (PLs), carbohydrate esterases (CEs), and glycosyltransferases (GTs) as well as carbohydrate-binding modules (CBMs) in the predicted proteomes of 103 representative fungi from Ascomycota, Basidiomycota, Chytridiomycota, and Zygomycota. Comparative analysis of these CAZymes that play major roles in plant polysaccharide degradation revealed that fungi exhibit tremendous diversity in the number and variety of CAZymes. Among them, some families of GHs and CEs are the most prevalent CAZymes that are distributed in all of the fungi analyzed. Importantly, cellulases of some GH families are present in fungi that are not known to have cellulose-degrading ability. In addition, our results also showed that in general, plant pathogenic fungi have the highest number of CAZymes. Biotrophic fungi tend to have fewer CAZymes than necrotrophic and hemibiotrophic fungi. Pathogens of dicots often contain more pectinases than fungi infecting monocots. Interestingly, besides yeasts, many saprophytic fungi that are highly active in degrading plant biomass contain fewer CAZymes than plant pathogenic fungi. Furthermore, analysis of the gene expression profile of the wheat scab fungus Fusarium graminearum revealed that most of the CAZyme genes related to cell wall degradation were up-regulated during plant infection. Phylogenetic analysis also revealed a complex history of lineage-specific expansions and attritions for the PL1 family.
conclusionsOur study provides insights into the variety and expansion of fungal CAZyme classes and revealed the relationship of CAZyme size and diversity with their nutritional strategy and host specificity.
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