ArticleJournal of the American Geriatrics Society2013
Nondisease-specific problems and all-cause mortality in the REasons for Geographic and Racial Differences in Stroke study.
Article in Journal of the American Geriatrics Society, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed.
- Dose-Response Relationships Between Polypharmacy and All-Cause and Cause-Specific Mortality Among Older People.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022Article
- The impact of high-risk medications on mortality risk among older adults with polypharmacy: evidence from the English Longitudinal Study of Ageing.BMC medicine · 2021Article
- Does sedentary time increase in older adults in the days following participation in intense exercise?Aging clinical and experimental research · 2020Article
- Article
- Reliability and Utility of the Surprise Question in CKD Stages 4 to 5.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2017Observational
- Caring for patients with kidney disease: shifting the paradigm from evidence-based medicine to patient-centered care.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2016Review
- Perceived Stress and Atrial Fibrillation: The REasons for Geographic and Racial Differences in Stroke Study.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2015Article
- Effect of Falls on Frequency of Atrial Fibrillation and Mortality Risk (from the REasons for Geographic And Racial Differences in Stroke Study).The American journal of cardiology · 2015Article
- Predicting mortality in older adults with kidney disease: a pragmatic prediction model.Journal of the American Geriatrics Society · 2015Article
- Nondisease-specific problems and all-cause mortality among older adults with CKD: the REGARDS Study.Clinical journal of the American Society of Nephrology : CJASN · 2014Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
objectivesTo evaluate the association between six nondisease-specific problems (problems that cross multiple domains of health) and mortality in middle-aged and older adults.
designProspective, observational cohort.
settingU.S. population sample.
participantsParticipants included 23,669 black and white U.S. adults aged 45 and older enrolled in the REasons for Geographic and Racial Differences in Stroke (REGARDS) study. MEASUREMENTS: Nondisease-specific problems included cognitive impairment, depressive symptoms, exhaustion, falls, impaired mobility, and polypharmacy. Age-stratified (<65, 65-74, ≥ 75) hazard ratios for all-cause mortality were calculated for each problem individually and according to number of problems.
resultsOne or more nondisease-specific problems occurred in 40% of participants younger than 65, 45% of those aged 65 to 74, and 55% of those aged 75 and older. Compared with participants with none of these problems, the multivariable adjusted hazard ratio for all-cause mortality associated with each additional nondisease-specific problem was 1.34 (95% confidence interval (CI) = 1.23-1.46) for participants younger than 65, 1.24 (95% CI = 1.15-1.35) for those aged 65 to 74, and 1.30 (95% CI = 1.21-1.39) for those aged 75 and older.
conclusionNondisease-specific problems were associated with mortality across a wide age spectrum. Future studies should explore whether treating these problems will improve survival and identify innovative healthcare models to address multiple nondisease-specific problems simultaneously.
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