ArticleBMC infectious diseases2013
Lactobacillus species isolated from vaginal secretions of healthy and bacterial vaginosis-intermediate Mexican women: a prospective study.
Article in BMC infectious diseases, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.
- The vaginal microbiota: what have we learned after a decade of molecular characterization?PloS one · 2014Pooled it
- The Vaginal Microbiome and Host Health: Implications for Cervical Cancer Progression.International journal of molecular sciences · 2026Review
- Evidence ofMicrobial genomics · 2024Article
- Simultaneous application of oral and intravaginal probiotics for Helicobacter pylori and its antibiotic-therapy-induced vaginal dysbacteriosis.NPJ biofilms and microbiomes · 2024Review
- Characterization of Vaginal Lactobacilli with Potential Probiotic Properties Isolated from Healthy Women in Northern Iran.Indian journal of microbiology · 2024Article
- Evaluation of inhibitory and probiotic properties of lactic acid bacteria isolated from vaginal microflora.Folia microbiologica · 2022Article
- The impact of contraceptives on the vaginal microbiome in the non-pregnant state.Frontiers in microbiomes · 2022Review
- Preliminary Identification of the Aerobic Cervicovaginal Microbiota in Mexican Women With Cervical Cancer as the First Step Towards Metagenomic Studies.Frontiers in cellular and infection microbiology · 2022Observational
- Vaginal microbiome: normalcy vs dysbiosis.Archives of microbiology · 2021Review
- Bacterial Vaginosis and Sexually Transmitted Infections in an HIV-Positive Cohort.Frontiers in reproductive health · 2021Article
- Review
- Development of a High-Resolution Single-Nucleotide Polymorphism Strain-Typing Assay Using Whole Genome-Based Analyses for theMicroorganisms · 2020Article
- Community State Types of Vaginal Microbiota and Four Types of Abnormal Vaginal Microbiota in Pregnant Korean Women.Frontiers in public health · 2020Article
- Association of gestational diabetes mellitus and abnormal vaginal flora with adverse pregnancy outcomes.Medicine · 2018Observational
- Vaginal Lactobacilli Induce Differentiation of Monocytic Precursors Toward Langerhans-like Cells:Frontiers in immunology · 2018Article
- Vaginal lactobacilli profile in pregnant women with normal & abnormal vaginal flora.The Indian journal of medical research · 2017Article
- Characterisation of probiotic properties in human vaginal lactobacilli strains.Microbial ecology in health and disease · 2016Article
- Lactobacillus species as biomarkers and agents that can promote various aspects of vaginal health.Frontiers in physiology · 2015Review
- Functional genomics of lactic acid bacteria: from food to health.Microbial cell factories · 2014Review
- Polyethylene glycol-based hydrogels for controlled release of the antimicrobial subtilosin for prophylaxis of bacterial vaginosis.Antimicrobial agents and chemotherapy · 2014Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLactobacillus jensenii, L. iners, L. crispatus and L. gasseri are the most frequently occurring lactobacilli in the vagina. However, the native species vary widely according to the studied population. The present study was performed to genetically determine the identity of Lactobacillus strains present in the vaginal discharge of healthy and bacterial vaginosis (BV) intermediate Mexican women.
methodsIn a prospective study, 31 strains preliminarily identified as Lactobacillus species were isolated from 21 samples collected from 105 non-pregnant Mexican women. The samples were classified into groups according to the Nugent score criteria proposed for detection of BV: normal (N), intermediate (I) and bacterial vaginosis (BV). We examined the isolates using culture-based methods as well as molecular analysis of the V1-V3 regions of the 16S rRNA gene. Enterobacterial repetitive intergenic consensus (ERIC) sequence analysis was performed to reject clones.
resultsClinical isolates (25/31) were classified into four groups based on sequencing and analysis of the 16S rRNA gene: L. acidophilus (14/25), L. reuteri (6/25), L. casei (4/25) and L. buchneri (1/25). The remaining six isolates were presumptively identified as Enterococcus species. Within the L. acidophilus group, L. gasseri was the most frequently isolated species, followed by L. jensenii and L. crispatus. L. fermentum, L. rhamnosus and L. brevis were also isolated, and were placed in the L. reuteri, L. casei and L. buchneri groups, respectively. ERIC profile analysis showed intraspecific variability amongst the L. gasseri and L. fermentum species.
conclusionsThese findings agree with previous studies showing that L. crispatus, L. gasseri and L. jensenii are consistently present in the healthy vaginal ecosystem. Additional species or phylotypes were detected in the vaginal microbiota of the non-pregnant Mexican (Hispanic-mestizo) population, and thus, these results further our understanding of vaginal lactobacilli colonisation and richness in this particular population.
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