ArticleThe Canadian journal of hospital pharmacy2013
Evaluation of an electrolyte repletion protocol for cardiac surgery intensive care patients.
Article in The Canadian journal of hospital pharmacy, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 26 citations in OpenAlex.
- Trial
- Supplementation of calcium, magnesium, phosphate, and potassium in critically ill patients: A multicenter cohort study.PloS one · 2026Article
- Practice Patterns and Outcomes of Potassium Repletion Thresholds during Critical Illness.Annals of the American Thoracic Society · 2024Article
- Evaluation of Perioperative Beta-Blockers and Factors Associated with Postoperative Atrial Fibrillation in Cardiac Surgery: A Single Center Experience.Reviews in cardiovascular medicine · 2023Article
- Guiding Efficient, Effective, and Patient-Oriented Electrolyte Replacement in Critical Care: An Artificial Intelligence Reinforcement Learning Approach.Journal of personalized medicine · 2022Article
- The Impact of Delayed Symptomatic Treatment Implementation in the Intensive Care Unit.Healthcare (Basel, Switzerland) · 2021Article
- Examination of Electrolyte Replacements in the ICU Utilizing MIMIC-III Dataset Demonstrates Redundant Replacement Patterns.Healthcare (Basel, Switzerland) · 2021Article
- Behavioural patterns of electrolyte repletion in intensive care units: lessons from a large electronic dataset.Scientific reports · 2018Article
- Potassium and Magnesium Supplementation Do Not Protect Against Atrial Fibrillation After Cardiac Operation: A Time-Matched Analysis.The Annals of thoracic surgery · 2016Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundImplementation of electrolyte repletion protocols to facilitate and ensure the safety of electrolyte control is common practice in intensive care units (ICUs). However, few protocols have been evaluated and validated.
objectiveTo evaluate the effectiveness and safety of an electrolyte repletion protocol in a large, homogeneous group of postoperative patients.
methodsA retrospective study of patients admitted to the surgical ICU following coronary artery bypass grafting or heart valve replacement was undertaken at the Centre hospitalier universitaire de Sherbrooke, a 682-bed tertiary care hospital in Sherbrooke, Quebec. The proportion of measured values for serum potassium concentration that were within the desired range was compared between patients treated according to the electrolyte repletion protocol and those treated with the traditional approach to electrolyte repletion. Management of magnesium, phosphorus, and ionized calcium balance was also compared. The incidence of cardiac arrhythmias was documented, and the safety of the electrolyte repletion protocol was evaluated by determining and comparing proportions of values for serum electrolyte concentration that were above the desired range.
resultsIn total, 627 patients were included in the study: 312 in the control group and 315 in the protocol group. The proportion of patients with 100% of morning values for serum potassium concentration within the normal range was significantly higher in the protocol group than in the control group (66.1% versus 56.8%; p = 0.018). In the protocol group, significantly more patients received one or more replacement doses of magnesium and phosphorus (p < 0.001). The proportions of serum electrolyte values above the normal range were similar between the 2 groups, and there was no difference in the incidence of cardiac arrhythmias.
conclusionsThe electrolyte repletion protocol was more efficacious than traditional electrolyte repletion in maintaining normal serum potassium concentration and was safe.
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