Evidence map›Paper›PMID 23616662›Full record

ArticleJournal of virology2013

Human papillomavirus types 16, 18, and 31 share similar endocytic requirements for entry.

Gilles Spoden, Lena Kühling, Nicole Cordes, Bettina Frenzel, Martin Sapp, Klaus Boller, Luise Florin, Mario Schelhaas

Abstract readComparative Study
In one paragraph

Article in Journal of virology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. HPV caught in the tetraspanin web?Medical microbiology and immunology · 2020
    Article
  15. Article
  16. The Role of Promyelocytic Leukemia Nuclear Bodies During HPV Infection.Frontiers in cellular and infection microbiology · 2020
    Review
  17. Review
  18. Article
  19. Review
  20. The endocytic trafficking pathway of oncogenic papillomaviruses.Papillomavirus research (Amsterdam, Netherlands) · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gilles SpodenDepartment of Medical Microbiology and Hygiene, University Medical Centre of the Johannes Gutenberg University, Mainz, Germany.
Lena Kühling
Nicole Cordes
Bettina Frenzel
Martin Sapp
Klaus Boller
Luise Florin
Mario Schelhaas

Funding

Cell surface events of human papillomavirus type 16 and 18 infectionR01AI081809 · NIAID · LOUISIANA STATE UNIV HSC SHREVEPORT · PI SAPP, MARTIN · 2009 to 2013
$1.8M
NIAID NIH HHS R01 AI081809
6 · The paper itself

Abstract

Human papillomavirus type 18 (HPV18), one of the HPVs with malignant potential, enters cells by an unknown endocytic mechanism. The key cellular requirements for HPV18 endocytosis were tested in comparison to those for HPV16 and -31 endocytoses. HPV18 (like HPV16 and -31) entry was independent of clathrin, caveolin, dynamin, and lipid rafts but required actin polymerization and tetraspanin CD151, and the viruses were routed to the same LAMP-1-positive compartment. Hence, the viruses shared similar cellular requirements for endocytic entry.

Indexed as

Virus InternalizationActinsDynamin IIElectrophoresis, Polyacrylamide GelEndocytosisHeLa CellsHuman papillomavirus 16Human papillomavirus 18Human papillomavirus 31HumansLysosomal-Associated Membrane Protein 1Lysosomal Membrane ProteinsMembrane MicrodomainsMicroscopy, ConfocalMicroscopy, ElectronMicroscopy, FluorescenceActinsDynamin IILAMP1 protein, humanLysosomal-Associated Membrane Protein 1Lysosomal Membrane ProteinsTetraspanin 24

Identifiers

PMID23616662
PMCPMC3700296

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.