Evidence map›Paper›PMID 23616602›Full record

ArticleCirculation. Heart failure2013

Forecasting the impact of heart failure in the United States: a policy statement from the American Heart Association.

Paul A Heidenreich, Nancy M Albert, Larry A Allen, David A Bluemke, Javed Butler, Gregg C Fonarow, John S Ikonomidis, Olga Khavjou, Marvin A Konstam, Thomas M Maddox and 10 more

11 registry-linked trialsOpen access · bronzeAbstract read
In one paragraph

Article in Circulation. Heart failure, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 11 registered trials, which are not on this map. Cited by 1,324 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1,324citing papers in PubMed, 9 pooled it
96.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05759000 unknown statusstarted 2023, after this paper: background citation

The Effect of Early Inpatient Initiation of Dapagliflozin on the Health-related Quality of Life of Patients With Heart Failure With All Range of Ejection Fraction: a Local Registry

Ran2023Enrolled100Registered outcomes12Posted comparisons0ConditionsHeart FailureArmsdapagliflozin
Open the trial in the graph
NCT02344576 nacompletednot on this mapstarted 2015, after this paper: background citation

A Multicenter Trial of a Shared Decision Support Intervention for Patients and Their Caregivers Offered Destination Therapy for End-Stage Heart Failure

TypeinterventionalSponsorUniversity of Colorado, DenverRan2015 to 2018Enrolled445ConditionsHeart Failure, Heart-assist DevicesArmsDT LVAD Decision Support Intervention
NCT02673073 phase2 / phase3unknown statusnot on this mapstarted 2016, after this paper: background citation

Self-Awareness of Symptoms, Signs and Medical Compliance Using a Patient Diary in Heart Failure Management (AWARE-HF)

TypeinterventionalSponsorSeoul National University Bundang HospitalRan2016 to 2019Enrolled1,220ConditionsHeart FailureArmsPatient's diary, Patient's education
NCT03615469 naterminatednot on this mapstarted 2018, after this paper: background citation

Building Strength Through Rehabilitation for Heart Failure Patients

TypeinterventionalSponsorIndiana UniversityRan2018 to 2020Enrolled15ConditionsHeart FailureArmsTranscutaneous electrical stimulation, Neuromuscular electrical stimulation
NCT04327596 naterminatednot on this mapstarted 2021, after this paper: background citation

Randomized Clinical Trial of Radiofrequency Ablation for Atrial Fibrillation in Patients With Heart Failure With Preserved Ejection Fraction for Reduced Healthcare Utilization

TypeinterventionalSponsorUniversity of RochesterRan2021 to 2021Enrolled2ConditionsHeart Failure With Preserved Ejection FractionArmsRF ablation of AF using CARTO 3 and a Thermocool ST SF ablation catheter
NCT04752462 nacompletednot on this mapstarted 2021, after this paper: background citation

Effect of Post-Discharge Telemedicine Motivational Enhancement Intervention in Heart Failure and Obstructive Sleep Apnea on Adherence and Health Outcomes

TypeinterventionalSponsorThe Cleveland ClinicRan2021 to 2025Enrolled75ConditionsAcute Decompensated Heart Failure, Obstructive Sleep Apnea, Motivational Enhancement, PAP AdherenceArmsTelemedicine Intensive Motivational Enhancement
NCT04757246 nawithdrawnnot on this mapstarted 2022, after this paper: background citation

RESPECT Heart Failure- RESpiratory Pattern Evaluation in Clinical Trials for HF

TypeinterventionalSponsorWakeMed Health and HospitalsRan2022 to 2022Enrolled0ConditionsHeart FailureArmsMouthLab Device
NCT05130008 nacompletednot on this mapstarted 2022, after this paper: background citation

Implementing a Digitally-enabled Community Health Worker Intervention for Patients With Heart Failure

TypeinterventionalSponsorMassachusetts General HospitalRan2022 to 2024Enrolled56ConditionsHeart Failure,CongestiveArmsDigitally-enabled CHW Care, Usual CHW Care
NCT05928026 nacompletednot on this mapstarted 2023, after this paper: background citation

Financial Support in an Underserved and Low-Income Population With Heart Failure

TypeinterventionalSponsorUniversity of Texas Southwestern Medical CenterRan2023 to 2025Enrolled153ConditionsHeart Failure, Systolic, Financial Stress, Medication Adherence, Quality of LifeArmsFinancial Support
NCT06921603 narecruitingnot on this mapstarted 2025, after this paper: background citation

Point-of-Care Ultrasound-Guided Diuresis for Acute Decompensated Heart Failure to Reduce 30-Day Readmissions and Acute Kidney Injury

TypeinterventionalSponsorUniversity of PittsburghRan2025 to 2026Enrolled588ConditionsHeart Decompensation, Acute, Acute Kidney InjuriesArmsFurosemide (Standard Diuretic) Treatment, POCUS-Assessed Diuretic Management
NCT07185100 recruitingnot on this mapstarted 2025, after this paper: background citation

A Prospective, Cross-sectional, Nationwide Community-based Observational Study to Determine the Prevalence of Unrecognized Heart Failure Among Patients at Risk in Urban Areas Across Germany Using CMR

TypeobservationalSponsorGerman Heart InstituteRan2025 to 2036Enrolled600ConditionsHeart Failure With Preserved Ejection Fraction (HFPEF), Renal Dysfunction, Stage B Heart Failure
3 · Its place in the literature

Who cites it

1,324 citing papers in PubMed, 9 syntheses or guidelines pooled it, 2,765 citations in OpenAlex.

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  17. PaOCJC open · 2026
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  18. Article
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  20. Analysis of serum NMR metabolomics in fibrotic diseases of the myocardium.Metabolomics : Official journal of the Metabolomic Society · 2026
    Article

1,264 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 2 institutions in 2 countries.

Paul A Heidenreich
Nancy M Albert
Larry A Allen
David A Bluemke
Javed Butler
Gregg C Fonarow
John S Ikonomidis
Olga Khavjou
Marvin A Konstam
Thomas M Maddox
Graham Nichol
Michael Pham
Ileana L Piña
Justin G Trogdon
American Heart Association Advocacy Coordinating Committee
Council on Arteriosclerosis, Thrombosis and Vascular Biology
Council on Cardiovascular Radiology and Intervention
Council on Clinical Cardiology
Council on Epidemiology and Prevention
Stroke Council
American Heart Association · USInstitute of Cardiology · PL

Funding

Molecular Biomedical Imaging Laboratory (NIBIB)ZIAEB000072 · NIBIB · NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING · PI BLUEMKE, DAVID · 2010 to 2017
$5.0M
Addressing Gaps in Longitudinal Heart Failure Pharmacotherapy to Reduce RehospitaK23HL105896 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI ALLEN, LARRY ALEXANDER · 2011 to 2015
$676k
Molecular Biomedical Imaging Laboratory (CC)ZIACL090019 · CLC · CLINICAL CENTER · PI JONES, ELIZABETH C. · 2010 to 2017
$0k
NHLBI NIH HHS K23 HL105896
6 · The paper itself

Abstract

backgroundHeart failure (HF) is an important contributor to both the burden and cost of national healthcare expenditures, with more older Americans hospitalized for HF than for any other medical condition. With the aging of the population, the impact of HF is expected to increase substantially. METHODS AND

resultsWe estimated future costs of HF by adapting a methodology developed by the American Heart Association to project the epidemiology and future costs of HF from 2012 to 2030 without double counting the costs attributed to comorbid conditions. The model assumes that HF prevalence will remain constant by age, sex, and race/ethnicity and that rising costs and technological innovation will continue at the same rate. By 2030, >8 million people in the United States (1 in every 33) will have HF. Between 2012 and 2030, real (2010$) total direct medical costs of HF are projected to increase from $21 billion to $53 billion. Total costs, including indirect costs for HF, are estimated to increase from $31 billion in 2012 to $70 billion in 2030. If one assumes all costs of cardiac care for HF patients are attributable to HF (no cost attribution to comorbid conditions), the 2030 projected cost estimates of treating patients with HF will be 3-fold higher ($160 billion in direct costs).

conclusionsThe estimated prevalence and cost of care for HF will increase markedly because of aging of the population. Strategies to prevent HF and improve the efficiency of care are needed.

Indexed as

Cost of IllnessAdultAmerican Heart AssociationComorbidityFemaleForecastingHeart FailureHospitalizationHumansIncomeMalePatient Care TeamPrevalenceRisk FactorsTerminal CareUnited StatesAHA Scientific Statementsheart failure

Identifiers

PMID23616602
PMCPMC3908895
OpenAlexW2126617656

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

and 5 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.