ArticlePlant molecular biology2013
A WRKY gene from Tamarix hispida, ThWRKY4, mediates abiotic stress responses by modulating reactive oxygen species and expression of stress-responsive genes.
Article in Plant molecular biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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44 citing papers in PubMed, 87 citations in OpenAlex.
- Functional Characterization of the Oat (International journal of molecular sciences · 2026Article
- Positive regulatory role of EuWRKY1 in the biosynthesis of Eucommia ulmoides rubber.Functional & integrative genomics · 2026Article
- Identification of WRKY transcription factors (TFs) in the recretohalophyte Tamarix chinensis and functional analysis of TcWRKY13 under salt stress.Plant cell reports · 2026Article
- DNA methylation variations induced by salt and alkali stresses and their differential responses inFrontiers in plant science · 2026Article
- Exploring Different Roles ofLife (Basel, Switzerland) · 2025Article
- Plant Immunity: At the Crossroads of Pathogen Perception and Defense Response.Plants (Basel, Switzerland) · 2024Review
- The Impact of Salinity on Crop Yields and the Confrontational Behavior of Transcriptional Regulators, Nanoparticles, and Antioxidant Defensive Mechanisms under Stressful Conditions: A Review.International journal of molecular sciences · 2024Review
- Overexpression of the Purple Perilla (International journal of molecular sciences · 2023Article
- Insights into the Transcriptomics of Crop Wild Relatives to Unravel the Salinity Stress Adaptive Mechanisms.International journal of molecular sciences · 2023Review
- Transcriptome analysis of response strategy in Hemerocallis fulva under drought stress.Genes & genomics · 2023Article
- Recent Progress on the Salt Tolerance Mechanisms and Application of Tamarisk.International journal of molecular sciences · 2022Review
- Study on the Role of Salicylic Acid in Watermelon-Resistant Fusarium Wilt under Different Growth Conditions.Plants (Basel, Switzerland) · 2022Article
- Study on the Role of Phytohormones in Resistance to WatermelonPlants (Basel, Switzerland) · 2022Article
- Genome wide identification and characterization of nodulation related genes in Arachis hypogaea.PloS one · 2022Article
- The regulatory role of abscisic acid on cadmium uptake, accumulation and translocation in plants.Frontiers in plant science · 2022Review
- CRISPR/Cas9-mediated mutagenesis of WRKY3 and WRKY4 function decreases salt and Me-JA stress tolerance in Arabidopsis thaliana.Molecular biology reports · 2021Article
- ThHSFA1 Confers Salt Stress Tolerance through Modulation of Reactive Oxygen Species Scavenging by Directly RegulatingInternational journal of molecular sciences · 2021Article
- Dehydration-Induced WRKY Transcriptional Factor MfWRKY70 ofBiomolecules · 2021Article
- Roles of hormones, calcium andForestry research · 2021Article
- Overexpression of transcription factor SlWRKY28 improved the tolerance of Populus davidiana × P. bolleana to alkaline salt stress.BMC genetics · 2020Article
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Authors and funding
8 authors at 2 institutions in 1 country.
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Abstract
WRKY transcription factors are involved in various biological processes, such as development, metabolism and responses to stress. However, their exact roles in abiotic stress tolerance are largely unknown. Here, we demonstrated a working model for the function of a WRKY gene (ThWRKY4) from Tamarix hispida in the stress response. ThWRKY4 is highly induced by abscisic acid (ABA), salt and drought in the early period of stress (stress for 3, 6, or 9 h), which can be regulated by ABF (ABRE binding factors) and Dof (DNA binding with one finger), and also can be crossregulated by other WRKYs and autoregulated as well. Overexpression of ThWRKY4 conferred tolerance to salt, oxidative and ABA treatment in transgenic plants. ThWRKY4 can improve the tolerance to salt and ABA treatment by improving activities of superoxide dismutase and peroxidase, decreasing levels of O2 (-) and H2O2, reducing electrolyte leakage, keeping the loss of chlorophyll, and protecting cells from death. Microarray analyses showed that overexpression of ThWRKY4 in Arabidopsis leads to 165 and 100 genes significantly up- and downregulated, respectively. Promoter scanning analysis revealed that ThWRKY4 regulates the gene expression via binding to W-box motifs present in their promoter regions. This study shows that ThWRKY4 functions as a transcription factor to positively modulate abiotic stress tolerances, and is involved in modulating reactive oxygen species.
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