ReviewSchizophrenia bulletin2013
Structural and functional neuroimaging studies in major depressive disorder with psychotic features: a critical review.
Review in Schizophrenia bulletin, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed.
- Brain metabolite levels in remitted psychotic depression with consideration of effects of antipsychotic medication.Brain imaging and behavior · 2024Trial
- Neurocognitive Graphs of First-Episode Schizophrenia and Major Depression Based on Cognitive Features.Neuroscience bulletin · 2018Trial
- Framing major depressive disorder as a condition of network imbalance at the compartment level: a proof-of-concept study.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- Unraveling the Role of the Blood-Brain Barrier in the Pathophysiology of Depression: Recent Advances and Future Perspectives.Molecular neurobiology · 2024Review
- Functional network characteristics in adolescent psychotic mood disorder: associations with symptom severity and treatment effects.European child & adolescent psychiatry · 2024Article
- Altered language network lateralization in euthymic bipolar patients: a pilot study.Translational psychiatry · 2022Article
- Individualized diagnosis of major depressive disorder via multivariate pattern analysis of thalamic sMRI features.BMC psychiatry · 2021Article
- Heterogeneity and Classification of Recent Onset Psychosis and Depression: A Multimodal Machine Learning Approach.Schizophrenia bulletin · 2021Article
- Brain imaging features in schizophrenia with co-occurring auditory verbal hallucinations and depressive symptoms-Implication for novel therapeutic strategies to alleviate the reciprocal deterioration.Brain and behavior · 2021Review
- Structural brain networks in remitted psychotic depression.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2020Article
- Psychiatric neuroimaging research in Brazil: historical overview, current challenges, and future opportunities.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) · 2020Article
- Distinct structural brain circuits indicate mood and apathy profiles in bipolar disorder.NeuroImage. Clinical · 2020Article
- Interaction of the Psychiatric Risk GeneFrontiers in cellular neuroscience · 2019Article
- Characterizing Rapid Fluctuations of Resting State Functional Connectivity in Demyelinating, Neurodegenerative, and Psychiatric Conditions: From Static to Time-Varying Analysis.Frontiers in neuroscience · 2019Review
- Disrupted Brain Entropy And Functional Connectivity Patterns Of Thalamic Subregions In Major Depressive Disorder.Neuropsychiatric disease and treatment · 2019Article
- MicroRNA132 associated multimodal neuroimaging patterns in unmedicated major depressive disorder.Brain : a journal of neurology · 2018Article
- Grey and white matter volumes either in treatment-naïve or hormone-treated transgender women: a voxel-based morphometry study.Scientific reports · 2018Article
- Depression and Schizophrenia: Cause, Consequence, or Trans-diagnostic Issue?Schizophrenia bulletin · 2017Review
- L-type CaThe Journal of physiology · 2016Review
- Unexplained Painful Physical Symptoms in Patients with Major Depressive Disorder: Prevalence, Pathophysiology and Management.CNS drugs · 2016Review
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The relationship between major depressive disorder with psychotic (MDDP) features and schizophrenia has long been recognized, and the neurobiological boundaries between these disorders can nowadays be investigated using neuroimaging techniques. This article provides a critical review of such studies, addressing how they support a dimensional approach to the nosology and pathophysiology of psychotic disorders. A proportion of neuroimaging studies carried out to date indicate that MDDP subjects display structural and functional abnormalities in some brain regions specifically implicated in the pathophysiology of mood disorders, such as the subgenual cingulate cortex. This reinforces the validity of the classification of MDDP in proximity to major depression without psychosis. There is some neuroimaging evidence that MDDP may be associated with additional brain abnormalities relative to nonpsychotic major depression although less prominently in comparison with findings from the neuroimaging literature on schizophrenia. Brain regions seen as critical both to emotional processing and to models of psychotic symptoms, such as the hippocampus, insula, and lateral prefrontal cortex, have been implicated in separate neuroimaging investigations of either schizophrenia or major depression, as well as in some studies that directly compared depressed patients with and without psychotic features. These brain regions are key targets for future studies designed to validate imaging phenotypes more firmly associated with MDDP, as well as to investigate the relationship between these phenotypes and possible etiological influences for MDDP.
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