ArticleRetina (Philadelphia, Pa.)2013
Selective cone photoreceptor injury in acute macular neuroretinopathy.
Article in Retina (Philadelphia, Pa.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 50 citations in OpenAlex.
- Ultra-high-resolution imaging of acute macular neuroretinopathy: a case report.American journal of ophthalmology case reports · 2026Article
- Adaptive optics cone arrangement in hydroxychloroquine users without signs of retinal toxicity based on current screening guidelines: a case-control study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Article
- Extracting spacing-derived estimates of rod density in healthy retinae.Biomedical optics express · 2023Article
- Deep Capillary Plexus Features in Acute Macular Neuroretinopathy: Novel Insights Based on the Anatomy of Henle Fiber Layer.Investigative ophthalmology & visual science · 2022Article
- Challenges Associated With Ellipsoid Zone Intensity Measurements Using Optical Coherence Tomography.Translational vision science & technology · 2021Article
- Evaluating seasonal changes of cone photoreceptor structure in the 13-lined ground squirrel.Vision research · 2019Article
- Article
- Projection-Resolved OCT Angiography of Microvascular Changes in Paracentral Acute Middle Maculopathy and Acute Macular Neuroretinopathy.Investigative ophthalmology & visual science · 2018Article
- Intraobserver Repeatability and Interobserver Reproducibility of Ellipsoid Zone Measurements in Retinitis Pigmentosa.Translational vision science & technology · 2018Article
- Dysflective cones: Visual function and cone reflectivity in long-term follow-up of acute bilateral foveolitis.American journal of ophthalmology case reports · 2017Article
- Photoreceptor-Based Biomarkers in AOSLO Retinal Imaging.Investigative ophthalmology & visual science · 2017Review
- Quantification of retinal layer thickness changes in acute macular neuroretinopathy.The British journal of ophthalmology · 2017Article
- Article
- Variation in rod and cone density from the fovea to the mid-periphery in healthy human retinas using adaptive optics scanning laser ophthalmoscopy.Eye (London, England) · 2016Article
- Cone Photoreceptor Structure in Patients With X-Linked Cone Dysfunction and Red-Green Color Vision Deficiency.Investigative ophthalmology & visual science · 2016Article
- Evaluating Descriptive Metrics of the Human Cone Mosaic.Investigative ophthalmology & visual science · 2016Article
- Assessing Photoreceptor Structure in Retinitis Pigmentosa and Usher Syndrome.Investigative ophthalmology & visual science · 2016Article
- The fundus photo has met its match: optical coherence tomography and adaptive optics ophthalmoscopy are here to stay.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2016Review
- Functional and high-resolution retinal imaging monitoring photoreceptor damage in acute macular neuroretinopathy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2016Article
- Parafoveal cone abnormalities and recovery on adaptive optics in posterior uveitis.American journal of ophthalmology case reports · 2016Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
purposeTo evaluate retinal structural and functional abnormalities in a patient with acute macular neuroretinopathy.
methodsAn adaptive optics scanning light ophthalmoscope was used to image the photoreceptor mosaic and assess rod and cone structure. Spectral-domain optical coherence tomography was used to examine retinal lamination. Microperimetry was used to assess function across the macula.
resultsMicroperimetry showed reduced function of localized areas within retinal lesions corresponding to subjective scotomas. Spectral-domain optical coherence tomography imaging revealed attenuation of two outer retinal bands typically thought to reflect photoreceptor structure. Adaptive optics scanning light ophthalmoscope images of the photoreceptor mosaic revealed a heterogeneous presentation within these lesions. There were areas containing non-waveguiding cones and other areas of decreased cone density where the remaining rods had expanded to fill in the vacant space. Within these lesions, cone densities were shown to be significantly lower than eccentricity-matched areas of normal retina, as well as accepted histologic measurements. A 6-month follow-up revealed no change in rod or cone structure.
conclusionImaging of acute macular neuroretinopathy using an adaptive optics scanning light ophthalmoscope shows a preferential disruption of cone photoreceptor structure within the region of decreased retinal sensitivity (as measured by microperimetry). Adaptive optics-based imaging tools provide a noninvasive way to assess photoreceptor structure at a level of detail that is not resolved by use of conventional spectral-domain optical coherence tomography or other clinical measures.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.