Evidence map›Paper›PMID 23614991›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2013

The acceptability and safety of the Shang Ring for adult male circumcision in Rakai, Uganda.

Godfrey Kigozi, Richard Musoke, Stephen Watya, Nehemiah Kighoma, Paschal Ssebbowa, David Serwadda, Fred Nalugoda, Frederick Makumbi, Philip Li, Richard Lee and 4 more

Registry-linked trialAbstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06273696 (Evaluation of the Acceptability and Safety of the ShangRing Device for Male Circumcision in Shinyanga, Tanzania), which is not on this map. Cited by 33 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06273696 completednot on this mapstarted 2019, after this paper: background citation

Evaluation of the Acceptability and Safety of the ShangRing Device for Male Circumcision in Shinyanga, Tanzania

Typeobservational_patient_registrySponsorIntraHealth InternationalRan2019 to 2019Enrolled575ConditionsPenile Infection, Penile Haematoma, Penile Bleeding, DeformityArmsShangRing
3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Trial
  6. Trial
  7. Trial
  8. Novel penile circumcision suturing devices versus the shang ring for adult male circumcision: a prospective study.International braz j urol : official journal of the Brazilian Society of Urology
    Trial
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Circumcision and its effects in Africa.Translational andrology and urology · 2017
    Review
  15. Trends in the Marginal Cost of Male Circumcision in Rural Rakai Uganda.Journal of acquired immune deficiency syndromes (1999) · 2016
    Article
  16. Article
  17. Innovative Methods of Male Circumcision for HIV Prevention-Getting the Right Evidence.Journal of acquired immune deficiency syndromes (1999) · 2016
    Article
  18. Article
  19. Article
  20. Surgical Outcomes of Newly Trained ShangRing Circumcision Providers.Journal of acquired immune deficiency syndromes (1999) · 2016
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Godfrey Kigozi*Rakai Health Sciences Program, Entebbe, Uganda; †Department of Urology, Mulago Hospital, Kampala, Uganda; ‡School of Public Health, Makerere University, Kampala, Uganda; §Department of Urology, Weill Cornell Medical College, Cornell University, New York, NY; ‖Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD; and ¶College of Health Sciences, Makerere University, Kampala, Uganda.
Richard Musoke
Stephen Watya
Nehemiah Kighoma
Paschal Ssebbowa
David Serwadda
Fred Nalugoda
Frederick Makumbi
Philip Li
Richard Lee
Marc Goldstein
Maria Wawer
Nelson Sewankambo
Ronald H Gray

Funding

Circumcision: HIV/STIs and behaviors in a RCT and post-RCT surveillance; RakaiU01AI075115 · NIAID · JOHNS HOPKINS UNIVERSITY · PI GRAY, RONALD H · 2007 to 2011
$9.3M
Enhanced Provision of Male Circumcision for HIV Prevention, Rakai, UgandaU01AI100031 · NIAID · JOHNS HOPKINS UNIVERSITY · PI GRAY, RONALD H · 2012 to 2014
$3.2M
NIAID NIH HHS U01 AI075115NIAID NIH HHS U01 AI100031NIAID NIH HHS UO1 AI075115-0451
6 · The paper itself

Abstract

objectivesMedical male circumcision (MMC) is recommended for HIV prevention in men. We assessed the acceptability and safety of the Shang Ring device compared with those of the dorsal slit method.

methodsHIV-negative, uncircumcised men aged 18 years or older who requested free MMC services in rural Rakai, Uganda, were informed about the Shang Ring and dorsal slit procedures and offered a free choice of procedure. Men were followed at 7 days postoperatively to assess adverse events related to surgery and to remove the Shang Ring. Wound healing was assessed at 4 weeks postoperatively.

resultsSix hundred twenty-one men were enrolled, of whom 508 (81.8%) chose the Shang Ring and 113 the dorsal slit. The Shang Ring was provided to 504 men, among whom there were 4 failures of Ring placement (0.8%) that required surgical hemostasis and wound closure. Five hundred men received the Shang Ring and postoperative surgery-related moderate adverse events were 1.0%, compared with 0.8% among dorsal slit recipients. Complete wound healing at 4 weeks was 84% with the Ring and 100% with the dorsal slit (P < 0001). Resumption of intercourse before 4 weeks was 7.0% with the Ring and 15.0% with the dorsal slit (P = 0.01.) The mean time for surgery was 6.1 minutes with the Ring and 17.7 minutes with the dorsal slit. The mean time for Ring removal was 2.2 minutes.

conclusionsThe Shang Ring is highly acceptable and safe in this setting, and could improve the efficiency of MMC services. However, back-up surgical services are needed in cases of Ring placement failures.

Indexed as

Patient Acceptance of Health CareAdultCircumcision, MaleHumansMaleMiddle AgedPostoperative ComplicationsUgandaWound HealingYoung Adult

Identifiers

PMID23614991
PMCPMC3805675

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.