Evidence map›Paper›PMID 23614876›Full record

ArticleThe Journal of organic chemistry2013

Exploration of fluorine chemistry at the multidisciplinary interface of chemistry and biology.

Iwao Ojima

Abstract read
In one paragraph

Article in The Journal of organic chemistry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
12.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 195 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. CFBeilstein journal of organic chemistry · 2021
    Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Stereocontrolled Synthesis of 2-FluorinatedEuropean journal of organic chemistry · 2018
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Chemical probes for the functionalization of polyketide intermediates.Angewandte Chemie (International ed. in English) · 2014
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Iwao OjimaDepartment of Chemistry and Institute of Chemical Biology & Drug Discovery, Stony Brook University, Stony Brook, New York 11794-3400, USA. iwao.ojima@stonybrook.edu
Stony Brook University · US

Funding

Tumor -Targeting Chemotherapeutic AgentsR01CA103314 · NCI · STATE UNIVERSITY NEW YORK STONY BROOK · PI OJIMA, IWAO · 2003 to 2013
$3.1M
NEW SYNTHESIS OF BIOCHEMICAL WITH HOMOGENEOUS CATALYSTSR01GM039226 · NIGMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI OJIMA, IWAO · 1988 to 2003
$772k
NON-PROTEIN AMINO ACIDS AND TAXOID ANTITUMOR AGENTSR01GM042798 · NIGMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI OJIMA, IWAO · 1990 to 2002
$622k
NCI NIH HHS R01 CA103314NIGMS NIH HHS R01 GM039226NIGMS NIH HHS R01 GM042798
6 · The paper itself

Abstract

Over the last three decades, my engagement in "fluorine chemistry" has evolved substantially because of the multidisciplinary nature of the research programs. I began my research career as a synthetic chemist in organometallic chemistry and homogeneous catalysis directed toward organic synthesis. Then, I was brought into a very unique world of "fluorine chemistry" in the end of 1970s. I started exploring the interface of fluorine chemistry and transition metal homogeneous catalysis first, which was followed by amino acids, peptides, and peptidomimetics for medicinal chemistry. Since then, I have been exploring the interfaces of fluorine chemistry and multidisciplinary fields of research involving medicinal chemistry, chemical biology, cancer biology, and molecular imaging. This perspective intends to cover my fruitful endeavor in the exploration of fluorine chemistry at the multidisciplinary interface of chemistry and biology in a chronological order to show the evolution of my research interest and strategy.

Indexed as

BiologyChemistryHydrocarbons, FluorinatedHydrocarbons, Fluorinated

Identifiers

PMID23614876
PMCPMC3752428
OpenAlexW2120436984

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.