Evidence map›Paper›PMID 23614576›Full record

ArticleJournal of computational biology : a journal of computational molecular cell biology2013

A new software package for predictive gene regulatory network modeling and redesign.

Emmanuel Faure, Isabelle S Peter, Eric H Davidson

Open access · hybridAbstract read
In one paragraph

Article in Journal of computational biology : a journal of computational molecular cell biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Eric Davidson's Regulatory Genome for Computer Science: Causality, Logic, and Proof Principles of the GenomicJournal of computational biology : a journal of computational molecular cell biology · 2019
    Article
  2. Article
  3. Article
  4. From blastocyst to gastrula: gene regulatory networks of embryonic stem cells and early mouse embryogenesis.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Emmanuel FaureDivision of Biology, MC 156-29, California Institute of Technology, Pasadena, California, USA. emmanuel.faure@polytechnique.edu
Isabelle S Peter
Eric H Davidson
California Institute of Technology · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The efficacy of a newly created software package for predictive modeling of developmental gene regulatory networks (GRNs) has recently been demonstrated (Peter et al., 2012 ). The program GeNeTool computes spatial gene expression patterns based on GRN interactions and thereby allows the direct comparison of predicted and observed spatial expression patterns. GeNeTool also permits in silico exploration of both cis- and trans- perturbations of GRN interactions. Here, we present this program, review briefly its major features and applications, and provide a detailed and accessible tutorial.

Indexed as

Gene Expression Regulation, DevelopmentalGene Regulatory NetworksModels, GeneticSoftware

Identifiers

PMID23614576
PMCPMC3667423
OpenAlexW1968871930

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.