Evidence map›Paper›PMID 23613763›Full record

ArticlePloS one2013

Approximate subgraph matching-based literature mining for biomedical events and relations.

Haibin Liu, Lawrence Hunter, Vlado Kešelj, Karin Verspoor

Abstract read
In one paragraph

Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. NegBio: a high-performance tool for negation and uncertainty detection in radiology reports.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2018
    Article
  11. Article
  12. Subgraph augmented non-negative tensor factorization (SANTF) for modeling clinical narrative text.Journal of the American Medical Informatics Association : JAMIA · 2015
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. An Overview of Biomolecular Event Extraction from Scientific Documents.Computational and mathematical methods in medicine · 2015
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Haibin LiuNational Center for Biotechnology Information, Bethesda, Maryland, United States of America. Haibin.Liu@nih.gov
Lawrence Hunter
Vlado Kešelj
Karin Verspoor

Funding

Computational Bioscience Program Training GrantT15LM009451 · NLM · UNIVERSITY OF COLORADO DENVER · PI Katherina Kechris-Mays, Arjun Krishnan · 2007 to 2026
$11.7M
Technology Development for a MolBio Knowledge-BaseR01LM008111 · NLM · UNIVERSITY OF COLORADO DENVER · PI HUNTER, LAWRENCE E · 2004 to 2021
$9.7M
Bio Text NLPR01LM009254 · NLM · UNIVERSITY OF COLORADO DENVER · PI HUNTER, LAWRENCE E · 2006 to 2018
$5.9M
Intramural NIH HHSNLM NIH HHS 5R01LM008111NLM NIH HHS 5R01LM009254NLM NIH HHS 5T15LM009451NLM NIH HHS R01 LM008111NLM NIH HHS R01 LM009254NLM NIH HHS T15 LM009451
6 · The paper itself

Abstract

The biomedical text mining community has focused on developing techniques to automatically extract important relations between biological components and semantic events involving genes or proteins from literature. In this paper, we propose a novel approach for mining relations and events in the biomedical literature using approximate subgraph matching. Extraction of such knowledge is performed by searching for an approximate subgraph isomorphism between key contextual dependencies and input sentence graphs. Our approach significantly increases the chance of retrieving relations or events encoded within complex dependency contexts by introducing error tolerance into the graph matching process, while maintaining the extraction precision at a high level. When evaluated on practical tasks, it achieves a 51.12% F-score in extracting nine types of biological events on the GE task of the BioNLP-ST 2011 and an 84.22% F-score in detecting protein-residue associations. The performance is comparable to the reported systems across these tasks, and thus demonstrates the generalizability of our proposed approach.

Indexed as

AlgorithmsBiomedical TechnologyPublicationsAmino AcidsDatabases, ProteinData MiningProteinsReproducibility of ResultsAmino AcidsProteins

Identifiers

PMID23613763
PMCPMC3629260

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.