ArticleGenomics & informatics2013
ENCODE: A Sourcebook of Epigenomes and Chromatin Language.
Article in Genomics & informatics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Review
- Genetic variants in the calcium signaling pathway participate in the pathogenesis of colorectal cancer through the tumor microenvironment.Frontiers in oncology · 2023Article
- Gal-2 Increases H3K4meBiomolecules · 2022Article
- The MHC in the era of next-generation sequencing: Implications for bridging structure with function.Human immunology · 2019Review
- Overlooked: Extrachromosomal DNA and Their Possible Impact on Whole Genome Sequencing.The Malaysian journal of medical sciences : MJMS · 2018Review
- Histone H3 Acetyl K9 and Histone H3 Tri Methyl K4 as Prognostic Markers for Patients with Cervical Cancer.International journal of molecular sciences · 2017Article
- Genetic Association Study ofBioMed research international · 2017Article
- Identification of the early and late responder genes during the generation of induced pluripotent stem cells from mouse fibroblasts.PloS one · 2017Article
- Altered expression of LINC-ROR in cancer cell lines and tissues.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2016Article
- Rheumatoid arthritis-associated RBPJ polymorphism alters memory CD4+ T cells.Human molecular genetics · 2016Article
- Common variants of NFE2L2 gene predisposes to acute respiratory distress syndrome in patients with severe sepsis.Critical care (London, England) · 2015Article
- Review
- A New Gene Therapy Approach for Cardiovascular Disease by Non-coding RNAs Acting in the Nucleus.Molecular therapy. Nucleic acids · 2014Review
- 1,25-Dihydroxyvitamin D3 induced histone profiles guide discovery of VDR action sites.The Journal of steroid biochemistry and molecular biology · 2014Review
- Genome-wide analysis of histone modifications in latently HIV-1 infected T cells.AIDS (London, England) · 2014Article
- Chromatin without the 30-nm fiber: constrained disorder instead of hierarchical folding.Epigenetics · 2014Review
- Epigenetics: relevance and implications for public health.Annual review of public health · 2014Review
- Integrated Bio-Search: challenges and trends for the integration, search and comprehensive processing of biological information.BMC bioinformatics · 2014Review
- Upregulation of adenylate cyclase 3 (ADCY3) increases the tumorigenic potential of cells by activating the CREB pathway.Oncotarget · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Until recently, since the Human Genome Project, the general view has been that the majority of the human genome is composed of junk DNA and has little or no selective advantage to the organism. Now we know that this conclusion is an oversimplification. In April 2003, the National Human Genome Research Institute (NHGRI) launched an international research consortium called Encyclopedia of DNA Elements (ENCODE) to uncover non-coding functional elements in the human genome. The result of this project has identified a set of new DNA regulatory elements, based on novel relationships among chromatin accessibility, histone modifications, nucleosome positioning, DNA methylation, transcription, and the occupancy of sequence-specific factors. The project gives us new insights into the organization and regulation of the human genome and epigenome. Here, we sought to summarize particular aspects of the ENCODE project and highlight the features and data that have recently been released. At the end of this review, we have summarized a case study we conducted using the ENCODE epigenome data.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.