ReviewWorld journal of gastroenterology2013
Is it worth investigating splenic function in patients with celiac disease?
Review in World journal of gastroenterology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 73 citations in OpenAlex.
- Article
- Risk of malignancy and surveillance of premalignant gastrointestinal lesions in adult celiac disease.Frontiers in oncology · 2026Review
- Vaccine Efficacy and Safety in Patients with Celiac Disease.Vaccines · 2024Review
- Phenotype and Treatment Options for Mesenteric Lymph Node Cavitating Syndrome in Coeliac Disease: A Case Series and Literature Review.Journal of clinical medicine · 2024Article
- Article
- Celiac Disease Presenting in a Community-Based Gastroenterology Practice: Obesity and Bone Disease Are Common.Digestive diseases and sciences · 2023Article
- A novel role of the splenic volume in Crohn's disease: evaluating the efficacy of infliximab.Frontiers in pharmacology · 2023Article
- Potential determinants of vaccine hesitancy among celiac disease patients: a single cohort analysis.Frontiers in public health · 2023Article
- Asplenia and spleen hypofunction.Nature reviews. Disease primers · 2022Review
- Vaccination Status and Attitudes towards Vaccines in a Cohort of Patients with Celiac Disease.Vaccines · 2022Article
- Integration of Distinct Analysis Strategies Improves Tissue-Trait Association Identification.Frontiers in genetics · 2022Article
- Human Babesiosis in Europe.Pathogens (Basel, Switzerland) · 2021Review
- Article
- Clinical Characteristics of Children With Celiac Disease Not Responding to Hepatitis B Vaccination in India.JPGN reports · 2021Article
- How to manage celiac disease and gluten-free diet during the COVID-19 era: proposals from a tertiary referral center in a high-incidence scenario.BMC gastroenterology · 2020Review
- COVID-19 pandemic perception in adults with celiac disease: an impulse to implement the use of telemedicine.Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver · 2020Article
- Article
- Vaccinations and Immune Response in Celiac Disease.Vaccines · 2020Review
- Clinical-Pathological Conference Series from the Medical University of Graz : Case No 169: A 32-year-old woman with anemia in pregnancy.Wiener klinische Wochenschrift · 2020Article
- Immunochip meta-analysis in European and Argentinian populations identifies two novel genetic loci associated with celiac disease.European journal of human genetics : EJHG · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Celiac disease, an immune-mediated enteropathy induced in genetically susceptible individuals by the ingestion of gluten, is the most frequent disorder associated with splenic hypofunction or atrophy. Defective splenic function affects more than one-third of adult patients with celiac disease, and it may predispose to a higher risk of infections by encapsulated bacteria and thromboembolic and autoimmune complications, particularly when celiac patients have concomitant pre-malignant and malignant complications (refractory celiac disease, ulcerative jejunoileitis and enteropathy-associated T-cell lymphoma). However, the clinical management of patients with celiac disease does not take into account the evaluation of splenic function, and in patients with high degree of hyposplenism or splenic atrophy the prophylactic immunization with specific vaccines against the polysaccharide antigens of encapsulated bacteria is not currently recommended. We critically re-evaluate clinical and diagnostic aspects of spleen dysfunction in celiac disease, and highlight new perspectives in the prophylactic management of infections in this condition.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.