ArticleWorld journal of gastroenterology2013
Colorectal anastomotic leakage: aspects of prevention, detection and treatment.
Article in World journal of gastroenterology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02589483 (RORA), which is not on this map. Cited by 56 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
RORA (Reinforcement of Rectal Anastomosis(<10cm) With HemoPatch - Pilot Study
Who cites it
56 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Robotic versus laparoscopic colectomy for transverse colon cancer: a systematic review and meta-analysis.International journal of colorectal disease · 2025Pooled it
- Surgical approaches to colonic and rectal anastomosis: systematic review and meta-analysis.International journal of colorectal disease · 2023Pooled it
- Is abdominal vascular calcification score valuable in predicting the occurrence of colorectal anastomotic leakage? A meta-analysis.International journal of colorectal disease · 2020Pooled it
- Virtual ileostomy in elective colorectal surgery: a systematic review of the literature.Techniques in coloproctology · 2020Pooled it
- Systematic review of endoluminal vacuum-assisted therapy as salvage treatment for rectal anastomotic leakage.BJS open · 2019Pooled it
- A nomogram for predicting 3-month mortality in colorectal cancer patients requiring perioperative ICU admission: a retrospective cohort study.World journal of surgical oncology · 2026Article
- Cytokines at the Crossroads of Mitochondrial Dysfunction and Inflammation in Colorectal Cancer: Implications for Postoperative Complications.Molecular diagnosis & therapy · 2026Review
- Hemopatch serosal reinforcement in right colectomy: transforming anastomotic leak patterns and severity compared to second-line suture technique-a 10-Year Retrospective Cohort Study of 352 patients.Updates in surgery · 2026Article
- Preoperative magnetic resonance imaging-based radiomics nomogram model for predicting postoperative anastomotic leakage in colorectal cancer.Annals of coloproctology · 2025Article
- Evaluation of intestinal wall closure using vessel-sealing technology versus conventional closure: an in vivo study.Surgery today · 2025Article
- Predictive Utility of Structured MRI Reporting for Rectal Cancer Outcomes.Diagnostics (Basel, Switzerland) · 2025Article
- TreatmENT of AnastomotiC LeakagE after colon cancer resection: the TENTACLE - Colon study.BMC surgery · 2025Article
- C-Reactive Protein in Peritoneal Fluid for Predicting Anastomotic Leakage After Colorectal Cancer Surgery: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2025Review
- The gut barrier as a gatekeeper in colorectal cancer treatment.Oncotarget · 2024Review
- [Postoperative Imaging Findings of Colorectal Surgery: A Pictorial Essay].Journal of the Korean Society of Radiology · 2024Review
- Clinical outcome and prognostic factors of T4N0M0 colon cancer after R0 resection: A retrospective study.World journal of gastrointestinal oncology · 2024Article
- Preservation of the inferior mesenteric artery VS ligation of the inferior mesenteric artery in left colectomy: evaluation of functional outcomes: a prospective non-randomized controlled trial.Updates in surgery · 2023Article
- Stoma-free survival after anastomotic leak following rectal cancer resection: worldwide cohort of 2470 patients.The British journal of surgery · 2023Article
- Evaluation of colonic anastomosis healing using hybrid nanosheets containing molybdenum disulfide (MOS2) scaffold of human placental amniotic membrane and polycaprolactone (PCL) in rat animal model.Naunyn-Schmiedeberg's archives of pharmacology · 2023Article
- Source control in emergency general surgery: WSES, GAIS, SIS-E, SIS-A guidelines.World journal of emergency surgery : WJES · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
All colorectal surgeons are faced from time to time with anastomotic leakage after colorectal surgery. This complication has been studied extensively without a significant reduction of incidence over the last 30 years. New techniques of prevention, by innovative anastomotic techniques should improve results in the future, but standardization and "teachability" should be guaranteed. Risk scoring enables intra-operative decision-making whether to restore continuity or deviate. Early detection can lead to reduction in delay of diagnosis as long as a standard system is used. For treatment options, no firm evidence is available, but future studies could focus on repair and saving of the anastomosis on the one hand or anastomotical breakdown and definitive colostomy on the other hand.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.