Changing the way we think about endothelial cell insulin sensitivity, nitric oxide, and the pathophysiology of type 2 diabetes: the FoxO is loose.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

9 citing papers in PubMed.

1. Cardiovascular profiling in the diabetic continuum: results from the population-based Gutenberg Health Study.Clinical research in cardiology : official journal of the German Cardiac Society · 2022
   Observational
2. Insulin-induced vascular redox dysregulation in human atherosclerosis is ameliorated by dipeptidyl peptidase 4 inhibition.Science translational medicine · 2020
   Article
3. Patient and Disease-Specific Induced Pluripotent Stem Cells for Discovery of Personalized Cardiovascular Drugs and Therapeutics.Pharmacological reviews · 2020
   Review
4. Endothelial Cell Metabolism.Physiological reviews · 2018
   Review
5. Endothelial APLNR regulates tissue fatty acid uptake and is essential for apelin's glucose-lowering effects.Science translational medicine · 2017
   Article
6. Specific insulin/IGF1 hybrid receptor activation assay reveals IGF1 as a more potent ligand than insulin.Scientific reports · 2015
   Article
7. New insights into insulin action and resistance in the vasculature.Annals of the New York Academy of Sciences · 2014
   Review
8. Comment on: Tessari et al. Roles of insulin, age, and asymmetric dimethylarginine on nitric oxide synthesis in vivo. Diabetes 2013;62:2699-2708.Diabetes · 2013
   Article
9. Response to comment on: Tessari et al. Roles of insulin, age, and asymmetric dimethylarginine on nitric oxide synthesis in vivo. Diabetes 2013;62:2699-2708.Diabetes · 2013
   Article

Corrections and comments

• Comment on
  Liver sinusoidal endothelial cells link hyperinsulinemia to hepatic insulin resistance.2013

Authors and funding

1 author.

Funding

Abstract

PubMed holds no abstract for this paper.

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