ArticleEnvironmental health perspectives2013
Cancer incidence in world trade center rescue and recovery workers, 2001-2008.
Article in Environmental health perspectives, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02246101 (Renal and Cardiovascular Impairment in WTC Responders), which is not on this map. Cited by 71 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Renal and Cardiovascular Impairment in WTC Responders: Implications for Diagnosis and Treatment
Who cites it
71 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Association Between Environmental Air Pollution and Thyroid Cancer and Nodules: A Systematic Review.Thyroid : official journal of the American Thyroid Association · 2024Pooled it
- World Trade Center disaster exposure-related probable posttraumatic stress disorder among responders and civilians: a meta-analysis.PloS one · 2014Pooled it
- Evolving Cancer Characteristics Among World Trade Center Survivors: An Updated Analysis from the WTC Environmental Health Center.International journal of environmental research and public health · 2026Article
- Lung Cancer Incidence After September 11, 2001, Among World Trade Center Responders.JAMA network open · 2025Article
- Epigenetic aging acceleration among World Trade Center-exposed community members.Scientific reports · 2025Article
- Importance of reference group selection in the evaluation of cancer incidence.Scientific reports · 2025Article
- Managing cancer following the World Trade Center disaster.Nature reviews. Cancer · 2024Article
- DNA Methylation as a Molecular Mechanism of Carcinogenesis in World Trade Center Dust Exposure: Insights from a Structured Literature Review.Biomolecules · 2024Review
- Genome-wide DNA methylation profiles and breast cancer among World Trade Center survivors.Environmental epidemiology (Philadelphia, Pa.) · 2024Article
- World Trade Center Exposure, DNA Methylation Changes, and Cancer: A Review of Current Evidence.Epigenomes · 2023Review
- Type 2 diabetes and thyroid cancer: Synergized risk with rising air pollution.World journal of diabetes · 2023Review
- TERT and BRAF V600E mutations in thyroid cancer of World Trade Center Responders.Carcinogenesis · 2023Article
- Mutagenicity of the organic fraction of World Trade Center dust.Environmental and molecular mutagenesis · 2023Article
- Characteristics of Cancers in Community Members Exposed to the World Trade Center Disaster at a Young Age.International journal of environmental research and public health · 2022Article
- Lung cancer incidence among world trade center rescue and recovery workers.Cancer medicine · 2022Article
- Posttraumatic Stress Disorder Mediates the Association between Traumatic World Trade Center Dust Cloud Exposure and Ongoing Systemic Inflammation in Community Members.International journal of environmental research and public health · 2022Article
- Cancer risk among World Trade Center rescue and recovery workers: A review.CA: a cancer journal for clinicians · 2022Review
- Global DNA methylation of WTC prostate cancer tissues show signature differences compared to non-exposed cases.Carcinogenesis · 2022Article
- Characteristics of Women with Lung Adenocarcinoma in the World Trade Center Environmental Health Center.International journal of environmental research and public health · 2022Article
- Global DNA Methylation Profiles in Peripheral Blood of WTC-Exposed Community Members with Breast Cancer.International journal of environmental research and public health · 2022Article
11 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
26 authors.
Funding
Abstract
backgroundWorld Trade Center (WTC) rescue and recovery workers were exposed to a complex mix of pollutants and carcinogens.
objectiveThe purpose of this investigation was to evaluate cancer incidence in responders during the first 7 years after 11 September 2001.
methodsCancers among 20,984 consented participants in the WTC Health Program were identified through linkage to state tumor registries in New York, New Jersey, Connecticut, and Pennsylvania. Standardized incidence ratios (SIRs) were calculated to compare cancers diagnosed in responders to predicted numbers for the general population. Multivariate regression models were used to estimate associations with degree of exposure.
resultsA total of 575 cancers were diagnosed in 552 individuals. Increases above registry-based expectations were noted for all cancer sites combined (SIR = 1.15; 95% CI: 1.06, 1.25), thyroid cancer (SIR = 2.39; 95% CI: 1.70, 3.27), prostate cancer (SIR = 1.21; 95% CI: 1.01, 1.44), combined hematopoietic and lymphoid cancers (SIR = 1.36; 95% CI: 1.07, 1.71), and soft tissue cancers (SIR = 2.26; 95% CI: 1.13, 4.05). When restricted to 302 cancers diagnosed ≥ 6 months after enrollment, the SIR for all cancers decreased to 1.06 (95% CI: 0.94, 1.18), but thyroid and prostate cancer diagnoses remained greater than expected. All cancers combined were increased in very highly exposed responders and among those exposed to significant amounts of dust, compared with responders who reported lower levels of exposure.
conclusionEstimates should be interpreted with caution given the short follow-up and long latency period for most cancers, the intensive medical surveillance of this cohort, and the small numbers of cancers at specific sites. However, our findings highlight the need for continued follow-up and surveillance of WTC responders.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.