ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2013
Predisposing factors for surgical site infection of spinal instrumentation surgery for diabetes patients.
Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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25 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.
- What are the risk factors for surgical site infection after spinal fusion? A meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2018Pooled it
- Association between smoking and surgical site infection after spinal fusion surgery: a systematic review and meta-analysis.Irish journal of medical science · 2026Article
- Development of Machine Learning Models for Predicting Surgical Site Infection After Spinal Surgery.Journal of clinical medicine · 2026Article
- Risk factors for surgical site infections after spinal surgery: a systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Review
- The impact of obesity, smoking and diabetes on the susceptibility to postoperative spinal infections: A risk-based approach.Bioinformation · 2026Article
- Effects of Pre-Operative HbA1c on Outcomes and the Rate of Clinical Improvement Following Anterior Cervical Discectomy and Fusion.Journal of clinical medicine · 2025Article
- Visceral fat: the hidden culprit behind thoracolumbar surgery infections.Frontiers in surgery · 2025Article
- Does type 2 diabetes affect the efficacy of therapeutic exercises for degenerative lumbar spinal stenosis?BMC musculoskeletal disorders · 2023Article
- Incidences and reasons of postoperative surgical site infection after lumbar spinal surgery: a large population study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2022Article
- Platelet-Derived Biomaterials Exert Chondroprotective and Chondroregenerative Effects on Diabetes Mellitus-Induced Intervertebral Disc Degeneration.Life (Basel, Switzerland) · 2021Article
- Implant Retention or Removal for Management of Surgical Site Infection After Spinal Surgery.Global spine journal · 2020Article
- Review
- Protective effect of intraoperative re-dose of prophylactic antibiotics on surgical site infection in diabetic patients: a retrospective cohort study.Annals of translational medicine · 2019Article
- Surgical Site Infection in Spine Surgery: Who Is at Risk?Global spine journal · 2018Article
- Comparison of Surgical Outcome Between Diabetic Versus Nondiabetic Patients After Lumbar Fusion.International journal of spine surgery · 2018Article
- Reoperation within 2 years after lumbar interbody fusion: a multicenter study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2018Article
- The effectiveness of pedicle screw immersion in vancomycin and ceftriaxone solution for the prevention of postoperative spinal infection: A prospective comparative study.Acta orthopaedica et traumatologica turcica · 2018Article
- Risk factors for surgical site infection following lumbar spinal surgery: a meta-analysis.Therapeutics and clinical risk management · 2018Article
- The effect of diabetes on perioperative complications following spinal surgery: a meta-analysis.Therapeutics and clinical risk management · 2018Article
- Cervical osteomyelitis with thoracic myelitis and meningitis in a diabetic patient.Clinical medicine insights. Case reports · 2015Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeDiabetes mellitus (DM) is known as an important risk factor for surgical site infection (SSI) in spine surgery. It is still unclear however which DM-related parameters have stronger influence on SSI. The purpose of this study is to determine predisposing factors for SSI following spinal instrumentation surgery for patients with DM.
methods110 DM patients (66 males and 44 females) who underwent spinal instrumentation surgery in one institute were enrolled in this study. For each patient, various preoperative or intraoperative parameters were reviewed from medical records. Patients were divided into two groups (SSI or non-SSI) based on the postoperative course. Each parameter between these two groups was compared. Univariate and multivariate analyses were performed to determine predisposing factor for SSI.
resultsThe SSI group consisted of 11 patients (10%), and the non-SSI group of 99 patients (90%). Univariate analysis revealed that preoperative proteinuria (p = 0.01), operation time (p = 0.04) and estimated blood loss (p = 0.02) were significantly higher in the SSI group compared to the non-SSI group. Multivariate logistic regression identified preoperative proteinuria as a statistically significant predictor of SSI (OR 6.28, 95% CI 1.58-25.0, p = 0.009).
conclusionsProteinuria is a significant predisposing factor for SSI in spinal instrumentation surgery for DM patients. DM patients with proteinuria who are likely to suffer latent nephropathy have a potential risk for SSI. For them less invasive surgery is recommended for spinal instrumentation. In this retrospective study, there was no significant difference of preoperative condition in glycemic control between the two groups.
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