ArticleMycopathologia2013
Evaluation of Paracoccidioides brasiliensis infection by gp 43 intradermal test in rural settlements in Central-West Brazil.
Article in Mycopathologia, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Genetic background and immune response in paracoccidioidomycosis: A systematic review and meta-analysis of single nucleotide variants.PLoS neglected tropical diseases · 2026Pooled it
- Talaromyces marneffei, Coccidioides species, and Paracoccidioides species-a systematic review to inform the World Health Organization priority list of fungal pathogens.Medical mycology · 2024Pooled it
- The Effect of Geoclimatic Factors on the Distribution of Paracoccidioidomycosis in Mato Grosso do Sul, Brazil.Journal of fungi (Basel, Switzerland) · 2024Article
- A Case-Control Study of Paracoccidioidomycosis in Women: The Hormonal Protection Revisited.Journal of fungi (Basel, Switzerland) · 2021Article
- Pathogenesis and Classification of Paracocidioidomycosis: New Insights From Old Good Stuff.Open forum infectious diseases · 2021Review
- An autochthonous case of paracoccidioidomycosis in a new area of Ceara State, Northeastern Brazil.Revista do Instituto de Medicina Tropical de Sao Paulo · 2019Article
- Standardization and Prevalence of the Booster Phenomenon: Evaluation Using a Two-Step Skin Test with 43 kDa Glycoprotein in Individuals from an Endemic Region of Paracoccidioidomycosis.Mycopathologia · 2017Article
- New Trends in Paracoccidioidomycosis Epidemiology.Journal of fungi (Basel, Switzerland) · 2017Review
- Paracoccidioidomycosis: Current Perspectives from Brazil.The open microbiology journal · 2017Review
- EPIDEMIOLOGY OF PARACOCCIDIOIDOMYCOSIS.Revista do Instituto de Medicina Tropical de Sao Paulo · 2015Article
- Phenotypic and functional evaluations of peripheral blood monocytes from chronic-form paracoccidioidomycosis patients before and after treatment.BMC infectious diseases · 2014Article
- Decreasing prevalence of the acute/subacute clinical form of paracoccidioidomycosis in Mato Grosso do Sul State, Brazil.Revista do Instituto de Medicina Tropical de Sao PauloObservational
- Prevalence of paracoccidioidomycosis infection by intradermal reaction in rural areas in Alfenas, Minas Gerais, Brazil.Revista do Instituto de Medicina Tropical de Sao PauloArticle
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Epidemiological studies of paracoccidioidomycosis have been based on surveys achieved with intradermal tests, and paracoccidioidin is the most common antigen used in most cases. The glycoprotein of 43-kDa (gp43) has been used in intradermal tests. It is the most antigenic component of Paracoccidioides brasiliensis, and it provides greater specificity to evaluate infection for this fungus. In this study, the prevalence of P. brasiliensis infection was estimated with intradermal tests involving gp43 for 695 people in rural Central-West Brazil. The infection rate was 45.8 % (95 % CI = 42.1-49.5), and the average age of those infected was 45.8 ± 18.2 years. The prevalence did not show gender-based differences but increased with age. The results demonstrate the importance of P. brasiliensis infection in rural settlements and the early exposure of children in the region to the fungus. Despite the high antigenicity and specificity of gp43, its usage must be standardized, so that epidemiological surveys will be comparable and more accurately reflect P. brasiliensis infection in endemic areas.
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