ArticleWorld journal of urology2013
Semen quality and associated reproductive indicators in middle-aged males: the role of non-malignant prostate conditions and genital tract inflammation.
Article in World journal of urology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 4 syntheses or guidelines pooled it, 21 citations in OpenAlex.
- Chronic prostatitis and its detrimental impact on sperm parameters: a systematic review and meta-analysis.Journal of endocrinological investigation · 2017Pooled it
- Zinc levels in seminal plasma and their correlation with male infertility: A systematic review and meta-analysis.Scientific reports · 2016Pooled it
- The effect of chronic bacterial prostatitis on semen quality in adult men: a meta-analysis of case-control studies.Scientific reports · 2014Pooled it
- Pooled it
- Trial
- Impaired Semen Quality in Patients with Chronic Prostatitis.Journal of clinical medicine · 2024Article
- Immune regulatory cytokines in seminal plasma of healthy men: A scoping review and analysis of variance.Andrology · 2023Article
- High altitude exposure affects male reproductive parameters: could it also affect the prostate?†.Biology of reproduction · 2022Review
- The efficacy and mechanism of acupuncture in the treatment of male infertility: A literature review.Frontiers in endocrinology · 2022Review
- Article
- [Infection and infertility].Der Urologe. Ausg. A · 2016Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo compare the associations between non-malignant prostate conditions, genital tract inflammation, and reproductive function in middle-aged men.
methodsThree-hundred and eighty-two voluntary male subjects who underwent the screening for prostate health were recruited for the study. Semen quality and associated reproductive indicators, seminal inflammation, and prostate-related pathologies were evaluated.
resultsSperm motility and prostate-related parameters were significantly impaired in patients with chronic prostatitis syndromes and lower urinary tract symptoms in comparison with controls. Elevated seminal markers of inflammation were in positive association with body mass index, prostate-specific antigen, and estradiol level in serum while in negative association with semen volume, total sperm count, and sperm motility. According to WHO reference limits, speculative cutoff values for WBC and IL-6 in semen to detect reduced sperm parameters were 0.342 M/mL and 56.8 ng/L, respectively.
conclusionsAccording to our data, one of the possible pathways for impaired reproductive quality in male subjects >45 years could be related to infection and inflammation in the genital tract with subsequent (partial) obstruction and damage of prostate and other male accessory glands.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.