Evidence map›Paper›PMID 23612517›Full record

ArticleEuropean journal of clinical nutrition2013

Early life risk factors of being overweight at 10 years of age: results of the German birth cohorts GINIplus and LISAplus.

Z Pei, C Flexeder, E Fuertes, E Thiering, B Koletzko, C Cramer, D Berdel, I Lehmann, C-P Bauer, J Heinrich and 1 more

Open access · hybridAbstract read
In one paragraph

Article in European journal of clinical nutrition, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Predicting childhood overweight and obesity using maternal and early life risk factors: a systematic review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2018
    Pooled it
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  16. Physical activity of German children during different segments of the school day.Zeitschrift fur Gesundheitswissenschaften = Journal of public health · 2017
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  19. Socioeconomic Status and Other Factors Associated with Childhood Obesity.Journal of the American Board of Family Medicine : JABFM
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Z PeiInstitute of Epidemiology I, Helmholtz Zentrum München, German Research Centre for Environmental Health, Neuherberg, Germany.
C Flexeder
E Fuertes
E Thiering
B Koletzko
C Cramer
D Berdel
I Lehmann
C-P Bauer
J Heinrich
GINIplus and LISAplus Study Group
Helmholtz Zentrum München · DEHelmholtz Centre for Environmental Research · DELeibniz Institute of Environmental Medicine · DEUniversity of British Columbia · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo develop a prediction model that quantifies the risk of being overweight at 10 years of age. SUBJECTS/

methodsIn total, 3121 participants from the GINIplus (German Infant Nutritional Intervention plus environmental and genetic influences on allergy development) and LISAplus (Influences of Lifestyle-Related Factors on the Immune System and the Development of Allergies in Childhood plus Air Pollution and Genetics) German birth cohorts were recruited. We predicted standardized body mass index (BMI) at 10 years of age using standardized BMIs from birth to 5 years. Parental education, family income and maternal smoking during pregnancy were considered as covariates. Linear and logistic regression models were used to evaluate the impact of risk factors on BMI and on being overweight at 10 years of age, respectively.

resultsBirth weight, standardized BMI at 5 years (60-64 months) (β=0.77; 95% confidence interval (CI): 0.73-0.81) and maternal smoking during pregnancy were positively associated with standardized BMI at 10 years of age. Standardized BMI and overweight at 5 years were strongest predictors of being overweight at 10 years. Conversely, high parental education conferred a protective effect (β=-0.15; 95% CI: -0.29 to -0.01). Being overweight at 5 years (60-64 months) increased the risk of being overweight at 10 years of age with odds ratios above 10. Among children who were predicted to be overweight at 10 years, cross-validation results showed that 76.8% of female subjects and 68.1% of male subjects would be overweight at 10 years of age.

conclusionBMI and being overweight at 5 years of age are strong predictors of being overweight at 10 years of age. The effectiveness of targeted interventions in children who are overweight at 5 years of age should be explored.

Indexed as

Birth WeightBody Mass IndexParentsPrenatal Exposure Delayed EffectsAge FactorsChildChild, PreschoolCohort StudiesEducational StatusFemaleGermanyHumansMaleObesityOdds RatioOverweight

Identifiers

PMID23612517
PMCPMC3736519
OpenAlexW1978868535

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.