ArticleNature communications2013
Identifying sources of tick blood meals using unidentified tandem mass spectral libraries.
Article in Nature communications, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed.
- Rodent-targeted approaches to reduce acarological risk of human exposure to pathogen-infected Ixodes ticks.Ticks and tick-borne diseases · 2023Review
- PhyloQuant approach provides insights into Trypanosoma cruzi evolution using a systems-wide mass spectrometry-based quantitative protein profile.Communications biology · 2021Article
- Retrotransposon-Based Blood Meal Analysis of Nymphal Deer Ticks Demonstrates Spatiotemporal Diversity of Borrelia burgdorferi and Babesia microti Reservoirs.Applied and environmental microbiology · 2021Article
- Virome and Blood Meal-Associated Host Responses inFrontiers in microbiology · 2021Article
- Host Bloodmeal Identification in Cave-DwellingFrontiers in veterinary science · 2021Article
- Identification of mixed and successive blood meals of mosquitoes using MALDI-TOF MS protein profiling.Parasitology · 2020Article
- Protein mass spectrometry detects multiple bloodmeals for enhanced Chagas disease vector ecology.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2019Article
- Pathogen proteotyping: A rapidly developing application of mass spectrometry to address clinical concerns.Clinical mass spectrometry (Del Mar, Calif.) · 2019Review
- A novel MALDI-TOF MS-based method for blood meal identification in insect vectors: A proof of concept study on phlebotomine sand flies.PLoS neglected tropical diseases · 2019Article
- Rapid detection of human blood in triatomines (kissing bugs) utilizing a lateral flow immunochromatographic assay - A pilot study.Memorias do Instituto Oswaldo Cruz · 2019Article
- Identification of closely related Ixodes species by protein profiling with MALDI-TOF mass spectrometry.PloS one · 2019Article
- Protein mass spectrometry extends temporal blood meal detection over polymerase chain reaction in mouse-fed Chagas disease vectors.Memorias do Instituto Oswaldo Cruz · 2018Article
- Future Prospects of Spectral Clustering Approaches in Proteomics.Proteomics · 2018Article
- Development of a Trypanosoma cruzi strain typing assay using MS2 peptide spectral libraries (Tc-STAMS2).PLoS neglected tropical diseases · 2018Article
- Multiflora rose invasion amplifies prevalence of Lyme disease pathogen, but not necessarily Lyme disease risk.Parasites & vectors · 2018Article
- Blood meal identification in the cryptic species Anopheles gambiae and Anopheles coluzzii using MALDI-TOF MS.Parasite (Paris, France) · 2018Article
- Article
- Ixodes persulcatus Ticks as Vectors for the Babesia microti U.S. Lineage in Japan.Applied and environmental microbiology · 2016Article
- Identification of blood meal sources in the main African malaria mosquito vector by MALDI-TOF MS.Malaria journal · 2016Article
- Top-down-assisted bottom-up method for homologous protein sequencing: hemoglobin from 33 bird species.Journal of the American Society for Mass Spectrometry · 2015Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Rapid and reliable identification of the vertebrate species on which a disease vector previously parasitized is imperative to study ecological factors that affect pathogen distribution and can aid the development of public health programs. Here we describe a proteome profiling technique designed to identify the source of blood meals of haematophagous arthropods. This method employs direct spectral matching and thus does not require a priori knowledge of any genetic or protein sequence information. Using this technology, we detect remnants of blood in blacklegged ticks (Ixodes scapularis) and correctly determine the vertebrate species from which the blood was derived, even 6 months after the tick had fed. This biological fingerprinting methodology is sensitive, fast, cost-effective and can potentially be adapted for other biological and medical applications when existing genome-based methods are impractical or ineffective.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.