Evidence map›Paper›PMID 23611614›Full record

ReviewSeminars in pediatric surgery2013

The role of growth factors in intestinal regeneration and repair in necrotizing enterocolitis.

Kathryn J Rowland, Pamela M Choi, Brad W Warner

Abstract readReview
In one paragraph

Review in Seminars in pediatric surgery, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 51 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Kathryn J RowlandDivision of Pediatric Surgery, St Louis Children's Hospital, St Louis, One's Children's Place, Suite 5540, Missouri 63110, USA.
Pamela M Choi
Brad W Warner
Washington University in St. Louis · US

Funding

ENTEROCYTE APOPTOSIS AFTER INTESTINAL RESECTIONR01DK059288 · NIDDK · WASHINGTON UNIVERSITY · PI WARNER, BRAD WAYNE · 2002 to 2011
$3.2M
INTESTINAL ADAPTATION AND EPIDERMAL GROWTH FACTORR01DK053234 · NIDDK · CINCINNATI CHILDRENS HOSP MED CTR · PI WARNER, BRAD WAYNE · 1998 to 2006
$1.7M
NIDDK NIH HHS R01 DK053234NIDDK NIH HHS R01 DK059288
6 · The paper itself

Abstract

Necrotizing enterocolitis (NEC) is a devastating intestinal disease resulting in major neonatal morbidity and mortality. The pathology is poorly understood, and the means of preventing and treating NEC are limited. Several endogenous growth factors have been identified as having important roles in intestinal growth as well as aiding intestinal repair from injury or inflammation. In this review, we will discuss several growth factors as mediators of intestinal regeneration and repair as well as potential therapeutic agents for NEC.

Indexed as

BiomarkersEnterocolitis, NecrotizingHumansInfant, NewbornInfant, PrematureInfant, Premature, DiseasesIntercellular Signaling Peptides and ProteinsIntestinal MucosaRegenerationBiomarkersIntercellular Signaling Peptides and Proteins

Identifiers

PMID23611614
PMCPMC3635039
OpenAlexW2154250835

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.