ArticleProceedings of the National Academy of Sciences of the United States of America2013
A 4-gigabase physical map unlocks the structure and evolution of the complex genome of Aegilops tauschii, the wheat D-genome progenitor.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 122 papers.
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Who cites it
122 citing papers in PubMed, 201 citations in OpenAlex.
- Direct avirulence effector-receptor interaction confers wheat immunity against insects.Science advances · 2026Article
- The Evolution and Origin of Allotetraploid Aegilops geniculata Revealed by the Homoeolog-Resolved Genome Assembly.Plant biotechnology journal · 2026Article
- Telomere-to-telomere genome assembly of linseed (Linum usitatissimum L.) for functional genomics and accelerated genetic improvement.Plant biotechnology journal · 2025Article
- Unveiling the evolutionary and transcriptional landscape of ERF transcription factors in wheat genomes: a genome-wide comparative analysis.BMC genomics · 2025Article
- Aegilops tauschii genome assembly v6.0 with improved sequence contiguity differentiates assembly errors from genuine differences with the D subgenome of Chinese Spring wheat assembly IWGSC RefSeq v2.1.G3 (Bethesda, Md.) · 2025Article
- Hill-Robertson interference may bias the inference of fitness effects of new mutations in highly selfing species.Evolution; international journal of organic evolution · 2025Article
- Hill-Robertson interference may bias the inference of fitness effects of new mutations in highly selfing species.bioRxiv : the preprint server for biology · 2024Article
- Wheat improvement through advances in single nucleotide polymorphism (SNP) detection and genotyping with a special emphasis on rust resistance.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Review
- Introgression of chromosome 5P from Agropyron cristatum enhances grain weight in a wheat background.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- An Accurate Representation of the Number of bZIP Transcription Factors in theCurrent issues in molecular biology · 2024Article
- Advances in the Mining of Disease Resistance Genes fromPlants (Basel, Switzerland) · 2023Review
- Wheat genomic study for genetic improvement of traits in China.Science China. Life sciences · 2022Review
- Haplotype variants of Sr46 in Aegilops tauschii, the diploid D genome progenitor of wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Article
- Evolution and origin of bread wheat.The Plant cell · 2022Article
- Progenitor species hold untapped diversity for potential climate-responsive traits for use in wheat breeding and crop improvement.Heredity · 2022Review
- Aegilops tauschii genome assembly Aet v5.0 features greater sequence contiguity and improved annotation.G3 (Bethesda, Md.) · 2021Article
- RNA-Seq-based DNA marker analysis of the genetics and molecular evolution of Triticeae species.Functional & integrative genomics · 2021Review
- Long-range assembly of sequences helps to unravel the genome structure and small variation of the wheat-Haynaldia villosa translocated chromosome 6VS.6AL.Plant biotechnology journal · 2021Article
- High-resolution mapping of the Mov-1 locus in wheat by combining radiation hybrid (RH) and recombination-based mapping approaches.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2021Article
- Introgressing the Aegilops tauschii genome into wheat as a basis for cereal improvement.Nature plants · 2021Article
62 more citing papers are in PubMed but not listed here.
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Authors and funding
31 authors at 14 institutions in 5 countries.
Funding
Abstract
The current limitations in genome sequencing technology require the construction of physical maps for high-quality draft sequences of large plant genomes, such as that of Aegilops tauschii, the wheat D-genome progenitor. To construct a physical map of the Ae. tauschii genome, we fingerprinted 461,706 bacterial artificial chromosome clones, assembled contigs, designed a 10K Ae. tauschii Infinium SNP array, constructed a 7,185-marker genetic map, and anchored on the map contigs totaling 4.03 Gb. Using whole genome shotgun reads, we extended the SNP marker sequences and found 17,093 genes and gene fragments. We showed that collinearity of the Ae. tauschii genes with Brachypodium distachyon, rice, and sorghum decreased with phylogenetic distance and that structural genome evolution rates have been high across all investigated lineages in subfamily Pooideae, including that of Brachypodieae. We obtained additional information about the evolution of the seven Triticeae chromosomes from 12 ancestral chromosomes and uncovered a pattern of centromere inactivation accompanying nested chromosome insertions in grasses. We showed that the density of noncollinear genes along the Ae. tauschii chromosomes positively correlates with recombination rates, suggested a cause, and showed that new genes, exemplified by disease resistance genes, are preferentially located in high-recombination chromosome regions.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.