ArticleProceedings of the National Academy of Sciences of the United States of America2013
Centrality in primate-parasite networks reveals the potential for the transmission of emerging infectious diseases to humans.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 2 of them syntheses that pooled it.
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Who cites it
52 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Diversity and transmission and zoonotic potential of microbes in true insectivores.Nature communications · 2025Pooled it
- Host phylogenetic distance drives trends in virus virulence and transmissibility across the animal-human interface.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019Pooled it
- Insectivores exhibit superior microbial network connectivity and elevated zoonotic risk by 2035 relative to rodents and bats.Science China. Life sciences · 2026Article
- Host Abundance Predicts Interactive Roles in Neotropical Bat-Bat Fly Interactions.Ecology and evolution · 2026Article
- Spreading potential in disease relevant networks: Predicting centralities in rural Northeast Madagascar.PLOS global public health · 2026Article
- A Hierarchical Niche Structure, Not Niche Partitioning, Organizes a Seasonally Dynamic Flea Community.Ecology and evolution · 2026Article
- Bayesian multiplex network models in R using STRAND: methods for biologists and social scientists.Royal Society open science · 2025Article
- Considerations for Social Networks and Health Data Sharing: An Overview.Annals of epidemiology · 2025Review
- Intestinal Parasitic Infections in Ghana: A Review of Infections and the Risk of Zoonotic Transmission.BioMed research international · 2025Review
- Bridging the Gap: Integrating Knowledge from the Study of Social Network Analysis and Infectious Disease Dynamics in Human and Nonhuman Primates.Annual review of anthropology · 2024Article
- A One Health framework for exploring zoonotic interactions demonstrated through a case study.Nature communications · 2024Article
- Ecto- and endoparasites of common reedbuck,Parasitology · 2024Article
- Occurrence of Free-Living Amoebae in Non-Human Primate Gut.Tropical medicine and infectious disease · 2024Article
- The evolution of same-sex sexual behaviour in mammals.Nature communications · 2023Article
- The heterogeneous herd: Drivers of close-contact variation in African buffalo and implications for pathogen invasion.Ecology and evolution · 2023Article
- Epidemiological connectivity between humans and animals across an urban landscape.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Impact of joint interactions with humans and social interactions with conspecifics on the risk of zooanthroponotic outbreaks among wildlife populations.Scientific reports · 2022Article
- Robust network stability of mosquitoes and human pathogens of medical importance.Parasites & vectors · 2022Review
- Review
- Challenges and Opportunities in the Use of High and Maximum Biocontainment Facilities in Developing and Licensing Risk Group 3 and Risk Group 4 Agent Veterinary Vaccines.ILAR journal · 2022Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Most emerging infectious diseases (EIDs) in humans have arisen from animals. Identifying high-risk hosts is therefore vital for the control and surveillance of these diseases. Viewing hosts as connected through the parasites they share, we use network tools to investigate predictors of parasitism and sources of future EIDs. We generated host-parasite networks that link hosts when they share a parasite, using nonhuman primates as a model system because--owing to their phylogenetic proximity and ecological overlap with humans--they are an important source of EIDs to humans. We then tested whether centrality in the network of host species--a measurement of the importance of a given node (i.e., host species) in the network--is associated with that host serving as a potential EID source. We found that centrality covaries with key predictors of parasitism, such as population density and geographic range size. Importantly, we also found that primate species having higher values of centrality in the primate-parasite network harbored more parasites identified as EIDs in humans and had parasite communities more similar to those found in humans. These relationships were robust to the use of different centrality metrics and to multiple ways of controlling for variation in how well each species has been studied (i.e., sampling effort). Centrality may therefore estimate the role of a host as a source of EIDs to humans in other multispecific host-parasite networks.
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