Evidence map›Paper›PMID 23610013›Full record

ArticleAngewandte Chemie (International ed. in English)2013

Supramolecular self-assembled nanoparticles mediate oral delivery of therapeutic TNF-α siRNA against systemic inflammation.

Lichen Yin, Ziyuan Song, Qiuhao Qu, Kyung Hoon Kim, Nan Zheng, Catherine Yao, Isthier Chaudhury, Haoyu Tang, Nathan P Gabrielson, Fatih M Uckun and 1 more

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Nanocapsule-mediated cytosolic siRNA delivery for anti-inflammatory treatment.Journal of controlled release : official journal of the Controlled Release Society · 2018
    Article
  11. Article
  12. Nonviral gene editing via CRISPR/Cas9 delivery by membrane-disruptive and endosomolytic helical polypeptide.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  13. Oral nucleic acid therapy using multicompartmental delivery systems.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2018
    Review
  14. Article
  15. Article
  16. SiRNA Crosslinked Nanoparticles for the Treatment of Inflammation-induced Liver Injury.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2017
    Article
  17. Helical antimicrobial polypeptides with radial amphiphilicity.Proceedings of the National Academy of Sciences of the United States of America · 2015
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lichen YinDepartment of Materials Science and Engineering, University of Illinois, Urbana-Champaign, 1304 West Green Street, Urbana, IL 61801, USA.
Ziyuan Song
Qiuhao Qu
Kyung Hoon Kim
Nan Zheng
Catherine Yao
Isthier Chaudhury
Haoyu Tang
Nathan P Gabrielson
Fatih M Uckun
Jianjun Cheng

Funding

Developing Clinically Applicable, Cancer-Targeting Polymeric NanoconjugatesDP2OD007246 · OD · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI CHENG, JIANJUN · 2010 to 2010
$2.4M
Development of Helical Polypeptides for Non-Viral Gene Delivery SystemsR21EB013379 · NIBIB · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI CHENG, JIANJUN · 2011 to 2012
$415k
NIBIB NIH HHS 1R21EB013379NIBIB NIH HHS R21 EB013379NIH HHS 1DP2OD007246NIH HHS DP2 OD007246
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Drug Delivery SystemsAdministration, OralAnimalsBase SequenceCell LineHumansInflammationMicroscopy, Electron, ScanningMolecular Sequence DataNanoparticlesParticle SizeRNA, Small InterferingTumor Necrosis Factor-alphaRNA, Small InterferingTumor Necrosis Factor-alpha

Identifiers

PMID23610013
PMCPMC3800743

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.