Evidence map›Paper›PMID 23609997›Full record

ArticleAngewandte Chemie (International ed. in English)2013

Direct synthesis of β-N-glycosides by the reductive glycosylation of azides with protected and native carbohydrate donors.

Jianbin Zheng, Kaveri Balan Urkalan, Seth B Herzon

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jianbin ZhengDepartment of Chemistry, Yale University, 225 Prospect Street, New Haven, CT 06520-8107, USA.
Kaveri Balan Urkalan
Seth B Herzon

Funding

Synthetic, Chemical Biological, and Preclinical Studies of Antitumor Natural Products and Their DerivativesR01GM090000 · NIGMS · YALE UNIVERSITY · PI HERZON, SETH B. · 2011 to 2018
$2.4M
NIGMS NIH HHS R01 GM090000NIGMS NIH HHS R01GM090000
6 · The paper itself

Abstract

A simple and straightforward method for the stereocontrolled synthesis of β-linked N-glycosides uses alkyl and aryl azides as the nitrogen source. The N-glycosides are formed in high yields and with high β selectivities (typically >70% yield, >15:1 β:α selectivity). This approach is also amenable to the synthesis of N-glycosylated amino acids and peptides (see example, Fmoc=9-fluorenylmethoxycarbonyl).

Indexed as

AzidesCarbohydratesGlycosidesGlycosylationAzidesCarbohydratesGlycosides

Identifiers

PMID23609997
PMCPMC4845733

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.