Evidence map›Paper›PMID 23609646›Full record

ArticleOptics express2013

Pump-probe nonlinear phase dispersion spectroscopy.

Francisco E Robles, Prathyush Samineni, Jesse W Wilson, Warren S Warren

Abstract read
In one paragraph

Article in Optics express, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Invited Review Article: Pump-probe microscopy.The Review of scientific instruments · 2016
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Francisco E RoblesDepartment of Chemistry, Duke University, Durham, North Carolina 27708, USA. francisco.robles@duke.edu
Prathyush Samineni
Jesse W Wilson
Warren S Warren

Funding

Improving Melanoma Diagnosis with Pump-Probe Optical ImagingR01CA166555 · NCI · DUKE UNIVERSITY · PI WARREN, WARREN S · 2013 to 2017
$1.6M
Imaging Nonlinear Absorption of Biomarkers for Improved Detection of MelanomaRC1CA145105 · NCI · DUKE UNIVERSITY · PI WARREN, WARREN S · 2009 to 2010
$998k
Novel Techniques in Nonlinear Optical Microscopy for Improving Melanoma DiagnosisF32CA168497 · NCI · DUKE UNIVERSITY · PI WILSON, JESSE WILLIAM · 2013 to 2015
$129k
NCI NIH HHS 1RC1CA145105NCI NIH HHS F32 CA168497NCI NIH HHS R01 CA166555NCI NIH HHS R01-CA166555NCI NIH HHS RC1 CA145105
6 · The paper itself

Abstract

Pump-probe microscopy is an imaging technique that delivers molecular contrast of pigmented samples. Here, we introduce pump-probe nonlinear phase dispersion spectroscopy (PP-NLDS), a method that leverages pump-probe microscopy and spectral-domain interferometry to ascertain information from dispersive and resonant nonlinear effects. PP-NLDS extends the information content to four dimensions (phase, amplitude, wavelength, and pump-probe time-delay) that yield unique insight into a wider range of nonlinear interactions compared to conventional methods. This results in the ability to provide highly specific molecular contrast of pigmented and non-pigmented samples. A theoretical framework is described, and experimental results and simulations illustrate the potential of this method. Implications for biomedical imaging are discussed.

Indexed as

Computer-Aided DesignEquipment DesignEquipment Failure AnalysisMicroscopyMolecular ImagingNonlinear DynamicsSpectrum Analysis

Identifiers

PMID23609646
PMCPMC3656694

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.